Evidence map›Paper›PMID 41087130›Full record

ReviewCanadian family physician Medecin de famille canadien2025

Anaplasmosis: Emerging threat in Canada.

Clarissa Ngo, Carol Koubaesh, Derek MacFadden, Pil Joo

Abstract readReview
In one paragraph

Review in Canadian family physician Medecin de famille canadien, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tick-borne anaplasmosis and myocarditis in eastern Ontario.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clarissa NgoFamily medicine resident at McMaster University in Hamilton, Ont. clarissa.ngo@medportal.ca.
Carol KoubaeshFamily medicine resident at the University of Ottawa in Ontario.
Derek MacFaddenInfectious diseases physician at the Ottawa Hospital and Assistant Professor in the Division of Infectious Diseases in the Department of Medicine at the University of Ottawa.
Pil JooFamily and emergency medicine physician at the Ottawa Hospital and Assistant Professor in the Department of Family Medicine at the University of Ottawa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide an overview of the diagnosis and management of patients with anaplasmosis, also known as SOURCES OF INFORMATION: A PubMed search was conducted between October 2024 and March 2025 using the search terms MAIN MESSAGE: Tick-borne illnesses are becoming more prevalent in Canada due to the effects of climate change. Anaplasmosis is a lesser-known tickborne illness transmitted by the same vectors as Lyme disease. Patients with anaplasmosis commonly present with a nonspecific febrile illness, often without a distinctive rash. Leukopenia, thrombocytopenia, and mild transaminitis are commonly seen in bloodwork results. Family physicians in Canada should familiarize themselves with this relatively new entity and include it in their differential diagnosis when evaluating patients with fever of unknown origin. In such cases, polymerase chain reaction testing for anaplasmosis, alongside Lyme disease serology, should be considered. Patients with either disease respond well to treatment with doxycycline.

conclusionWith the expanding range of tick populations in Canada, the risk of anaplasmosis, along with other tick-borne illnesses, is becoming more prevalent. Increased awareness among family physicians is critical for timely diagnosis. Prompt recognition and treatment can reduce the risk of complications.

Indexed as

AnaplasmosisCommunicable Diseases, EmergingTick-Borne DiseasesAnimalsAnti-Bacterial AgentsCanadaDoxycyclineHumansAnti-Bacterial AgentsDoxycycline

Identifiers

PMID41087130
PMCPMC12519968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.