Evidence map›Paper›PMID 41087066›Full record

ArticleSaudi medical journal2025

An evaluation of pharmaceutical clinical trials from Saudi Arabia registered on Clinicaltrials.gov: A cross-sectional study.

Mohammad H Aljawadi, Khalid F Alonazi, Ibrahim M Alsultan, Nora A Kalagi, Marwan A Alrasheed, Abdullah M Alhammad

Abstract read
In one paragraph

Article in Saudi medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad H AljawadiFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID https://orcid.org/0000-0002-5114-1343
Khalid F AlonaziFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Ibrahim M AlsultanFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Nora A KalagiFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Marwan A AlrasheedFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Abdullah M AlhammadFrom the Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate clinical trials involving pharmaceutical agents conducted in Saudi Arabia and registered on ClinicalTrials.gov. Since the early 2000s, Saudi Arabia has expanded its involvement in clinical research. Recognizing the importance of clinical trials, we aimed to analyze the clinical trial landscape in the Kingdom to identify well-covered areas and potential gaps.

methodsIn this descriptive cross-sectional study, ClinicalTrials.gov was used as the primary source to collect data regarding pharmacological and biological interventions conducted in Saudi Arabia between 2002 and June 2025.

resultsA total of 474 pharmaceutical studies were included. Of these, 52.95% were completed, indicating moderate research activity but suggesting room for growth compared to global benchmarks. Among completed trials, 38.64% had their results published on ClinicalTrials.gov. Overall, 223 sponsors were identified: 23.32% were international pharmaceutical companies and 24.22% were Saudi sponsors, of which 77.78% were governmental and 22.22% private. Additionally, 239 studies were funded by international companies. Oncology (23.21%) was the most represented medical field, followed by infectious diseases (12.87%).

conclusionSaudi Arabia witnessed an increase in registered clinical trials between 2002 and June 2025, with strong contributions from both international and Saudi sponsors, particularly the governmental sector. However, only one-fifth of completed trials had results published on ClinicalTrials.gov, highlighting the need for greater transparency and dissemination of findings.

Indexed as

Clinical Trials as TopicCross-Sectional StudiesHumansSaudi Arabiaclinical trial qualityClinical trialsclinical trials sponsorsSaudi Arabia

Identifiers

PMID41087066
PMCPMC12541733

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.