Evidence map›Paper›PMID 41087008›Full record

ArticleJMIR research protocols2025

Attitudes Toward Alternative Tobacco and Nicotine Products and Their Association With Lifestyle Habits: Protocol for the MINERVA International Observational Cohort Study.

Dario Gregori, Honoria Ocagli, Noor Muhammad Khan, Giulia Lorenzoni, Konstantina Thaleia Pilali, Ester Rosa, Francesca Angioletti, Aslıhan Şentürk Acar, Paola Berchialla, Danila Azzolina and 1 more

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dario Gregori *Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0000-0001-7906-0580
Honoria Ocagli *Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0000-0002-5823-1659
Noor Muhammad KhanUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0000-0003-4713-7277
Giulia LorenzoniUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0000-0003-1771-4686
Konstantina Thaleia PilaliUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0009-0009-3582-3633
Ester RosaUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0009-0002-5812-501X
Francesca AngiolettiUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0009-0004-1146-8693
Aslıhan Şentürk AcarDepartment of Actuarial Sciences, Beytepe, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-1708-2028
Paola BerchiallaDepartment of Clinical and Biological Sciences, Torino University, Torino, Italy.ORCID 0000-0001-5835-5638
Danila Azzolina *Department of Environmental Science and Prevention, Ferrara University, Ferrara, Italy.ORCID 0000-0002-8185-5742
Matteo Martinato *Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.ORCID 0000-0001-8875-1738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional smoking is widely recognized as a public health issue, with established risks that include cardiovascular, respiratory, and cancer-related health impacts. Recently, alternative tobacco and nicotine products (ATNPs), such as electronic cigarettes, have gained popularity as potentially safer substitutes for traditional tobacco use. However, there remains uncertainty regarding the health effects of ATNPs, which require comprehensive research to evaluate their risks and potential benefits compared to conventional smoking.

objectiveThe aim of this multicenter observational study, MINERVA (My Changing Lifestyles Our Research and Everyone Health), is to examine the interplay between traditional smoking and the potential effect of switching to ATNPs in culturally diverse European countries.

methodsData collection will be conducted through a structured web-based questionnaire and administered using a snowball sampling technique, which relies on the referrals and network connections of initial participants. A link will be provided for participants to access the questionnaire. Responders who express a willingness to participate in the study cohort will be recontacted at least twice a year to ensure continuity in their participation, and they will be asked to complete the same questionnaire during these follow-up assessments. This approach allows for the gathering of useful information over an extended period and the assessment of any changes or trends in the data that may emerge over time. Using social media for data collection, the research explores real-time attitudes and experiences related to smoking, with a particular focus on participants' receptiveness to transitioning to nonconventional tobacco products. Statistical analysis will include descriptive statistics, and logistic regression models will examine associations. Nonlinear trends will be assessed using restricted cubic splines. Analyses will be conducted in R software with relevant statistical packages.

resultsThe MINERVA study began in June 2023, and data collection is still in progress. As of January 2025, 7535 participants had been enrolled in Italy, of whom 4862 have consented to a follow-up. Preliminary analyses are currently being conducted.

conclusionsThe study underscores the importance of ongoing research to inform evidence-based policies and interventions, emphasizing the role of social media surveys in capturing diverse perspectives and facilitating longitudinal studies for a deeper understanding of the health implications of transitioning from traditional smoking to ATNPs. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/67163.

Indexed as

Life StyleSmokingTobacco ProductsAdultCohort StudiesElectronic Nicotine Delivery SystemsEuropeFemaleHumansMaleObservational Studies as TopicSurveys and Questionnairesalternative tobacco and nicotine productslifestylesmokingsurveyswitch

Identifiers

PMID41087008
PMCPMC12569482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.