Evidence map›Paper›PMID 41086553›Full record

ArticlePsychiatry research2025

The impact of trauma exposure on psychiatric symptoms and treatment of eating disorders in adolescents.

Natalie A Noebel, Jayme M Palka, Vivianne Oyefusi, Jasmine Ghannadpour, Urszula Kelley, Carrie J McAdams

Abstract read
In one paragraph

Article in Psychiatry research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie A NoebelDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA.
Jayme M PalkaDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA.
Vivianne OyefusiDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA.
Jasmine GhannadpourDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA; Center for Pediatric Eating Disorders, Children's Health, 7601 Preston Rd, Plano, TX, USA.
Urszula KelleyDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA; Center for Pediatric Eating Disorders, Children's Health, 7601 Preston Rd, Plano, TX, USA.
Carrie J McAdamsDepartment of Psychiatry, University of Texas Southwestern Medical Center, 1440 Empire Plaza DL4.228, Dallas, TX 75247, USA; Center for Pediatric Eating Disorders, Children's Health, 7601 Preston Rd, Plano, TX, USA. Electronic address: carrie.mcadams@utsouthwestern.edu.

Funding

UT Southwestern Center for Translational MedicineUL1TR003163 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2021 to 2025
$39.3M
Social Processes in Adolescent Anorexia NervosaR21MH131865 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI MCADAMS, CARRIE JUSTINE · 2023 to 2024
$482k
NCATS NIH HHS UL1 TR003163NIMH NIH HHS R21 MH131865
6 · The paper itself

Abstract

Potentially traumatic experiences are associated with eating disorders (ED). This study characterizes trauma exposures in a clinical adolescent ED population, considering types and impact on clinical course. Adolescents admitted for inpatient or partial hospitalization ED treatment completed ED, anxiety and depression questionnaires at intake and discharge. At intake, a Trauma Screener was completed, and if positive, the Childhood Posttraumatic Symptom Scale (CPSS-5-SR) was also completed. Participants were grouped based on number of trauma exposures reported (none, single, multiple), and linear mixed effects models considered how trauma impacted treatment responses. Study participants (n = 407) were 15.11 ± 1.59 years old, primarily female (86.5%), white (76.7%), and not-Hispanic (60.7%). Most reported trauma exposures (none 40.2%; single 17.0%; multiple 42.8%) with vicarious (36.8%), medical (25.2%), and physical (23.9%) most frequent. However, adolescents more commonly associated their symptoms with emotional (30.5%), medical (19.7%), or sexual (16.8%) trauma exposures. At intake, those with multiple trauma exposures had significantly higher depression, anxiety, and EDE-Q total and subscale scores (all p ≤ 0.003), except for restraint. Irrespective of trauma exposures, depression, eating, and anxiety improved with treatment (all p ≤ 0.003). Interactions with time and trauma were significant for depression (p = 0.04) and eating symptoms (p < .02), except restraint. These findings confirm that childhood trauma exposures are both extremely common in ED and increase psychiatric symptoms at presentation. Clinicians should consider screening adolescents presenting with trauma exposures for disordered eating, as earlier interventions for ED are known to improve outcomes.

Indexed as

Adverse childhood experiencesBinge-eatingBulimia nervosaChild psychiatryMood disordersPTSD

Identifiers

PMID41086553
PMCPMC13527816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.