Evidence map›Paper›PMID 41086279›Full record

SynthesisMedicina oral, patologia oral y cirugia bucal2025

Radiological features of double and inverted mesiodens: a systematic review of the literature and presentation of two cases.

A Lo-Casto, V Panzarella, E Palizzolo, R Mauceri, G Giuliana, F Bencivinni, G La-Mantia, G Campisi, M De-Angelis, G La-Tona and 1 more

Abstract readSystematic ReviewCase Reports
In one paragraph

Synthesis in Medicina oral, patologia oral y cirugia bucal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A Lo-CastoDepartment of Precision Medicine in Medical Surgical and Critical Care (Me.Pre.C.C.) Palermo, Italy rodolfo.mauceri@unipa.it.
V Panzarella
E Palizzolo
R Mauceri
G Giuliana
F Bencivinni
G La-Mantia
G Campisi
M De-Angelis
G La-Tona
O Di-Fede

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMesiodens are the most prevalent supernumerary teeth, defined as a dentition anomaly. Mesiodens account for 80% of all supernumerary teeth, with a prevalence in the general population of 0.15% -1.9%. Mesiodens show a higher frequency in man than in women, it is usually found in the front upper jaw, between the midlines of maxillary central teeth. It may be normally oriented or have inverted and transverse orientation. Single or multiple mesiodens may occur; however, double mesiodens is rarer (10-19% of all patients with mesiodens), and even rarer is its double inversion, with the crown and root oriented towards the nasal and oral cavities. The aim of this study is to investigate the main cone-beam computed tomography (CBCT) radiological features of patients affected by mesiodens. Two cases of double mesiodens, one of which with double inversion, in pediatric patients are reported. MATERIAL AND

methodsAccording to PRISMA guidelines, a systematic review search was conducted on PubMed, Scopus, and Web of Science. Observational studies conducted on patients with double mesiodens were selected and analyzed, including both radiological features and clinical characteristics. Furthermore, two cases of patients with double mesiodens were reported.

resultsFourteen studies were included, and 14 patients affected by double mesiodens were analyzed (12 males, 2 females, with a mean age of 13.5 ± 6.4 years).

conclusionsThe present study underscores the importance of considering the CBCT a fundamental investigation to define and appropriate diagnosis and management, and to avoid complications related to a late diagnosis and/or an unnecessary surgical approach.

Indexed as

Cone-Beam Computed TomographyTooth, SupernumeraryAdolescentChildFemaleHumansMale

Identifiers

PMID41086279
PMCPMC12579951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.