Evidence map›Paper›PMID 41086273›Full record

Trial reportMedicina oral, patologia oral y cirugia bucal2026

Analgesic efficacy of meloxicam vs ibuprofen on pain after third molar surgery in adult patients. A randomized controlled clinical trial.

R Falcón-Perez, V Pradenas-Loaiza, C Bertrán-Delgado, F Aguilera, J Kunstmann-Camino

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R Falcón-PerezSchool of Dentistry, Faculty of Medicine Universidad Austral de Chile Rudloff 1640. Sector Regional, Valdivia, Chile carla.bertran@uach.cl.
V Pradenas-Loaiza
C Bertrán-Delgado
F Aguilera
J Kunstmann-Camino

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis randomized clinical trial was designed to evaluate the postoperative analgesic efficacy of ibuprofen compared to meloxicam in patients undergoing third molar extraction. MATERIAL AND

methodsSixty-eight patients who had been indicated for the extraction of both a maxillary (semi-erupted or fully erupted crown) and mandibular third molar (Class I, Position A, and Class I, Position B, according to Pell and Gregory's classification) were randomly assigned to receive either meloxicam (7.5 mg every 12 hours, n = 34) or ibuprofen (400 mg every 8 hours, n = 34) following a single surgical procedure. Postoperative pain intensity was assessed using a Visual Analog Scale (VAS). All outcome measures were recorded during the first seven consecutive postoperative hours, and subsequently at 24, 48, and 72 hours. Addition, the presence or absence of adverse effects was recorded.

resultsIn this clinical trial, a total of 68 patients (mean age 24.7 years) completed the study in this clinical trial, and no patients were lost to follow-up. The results showed lower pain intensity in the ibuprofen-treated group at all evaluated time points, except at 72 hours; however, statistically significant differences were observed only at the 2-hour mark (p < 0.05). Both groups exhibited a sustained decrease in pain from 24 hours postoperatively onward (VAS < 2). Only two cases of mild dizziness were reported in the ibuprofen group.

conclusionsThese findings suggest that both therapeutic regimens are effective and well-tolerated options for postoperative pain management in third molar extraction.

Indexed as

Analgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalIbuprofenMeloxicamMolar, ThirdPostoperative PainTooth ExtractionAdolescentAdultFemaleHumansMaleYoung AdultAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalIbuprofenMeloxicam

Identifiers

PMID41086273
PMCPMC12743381

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.