Evidence map›Paper›PMID 41086242›Full record

ArticlePloS one2025

Psychological distress and wellbeing as mediators between anti-mattering (feelings of insignificance) and irritability among Lebanese adolescents: A cross-sectional study.

Michelle Abi Karam, Rabih Hallit, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Feten Fekih-Romdhane, Sahar Obeid, Souheil Hallit

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Michelle Abi KaramSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.
Rabih HallitSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.
Diana MalaebCollege of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates.
Fouad SakrSchool of Pharmacy, Lebanese International University, Beirut, Lebanon.ORCID https://orcid.org/0000-0002-6905-5814
Mariam DabbousSchool of Pharmacy, Lebanese International University, Beirut, Lebanon.
Feten Fekih-RomdhaneDepartment of Psychiatry "Ibn Omrane", The Tunisian Center of Early Intervention in Psychosis, Razi hospital, Manouba, Tunisia.
Sahar ObeidSchool of Arts and Sciences, Social and Education Sciences Department, Lebanese American University, Jbeil, Lebanon.ORCID https://orcid.org/0000-0002-0735-4704
Souheil HallitSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study examined the mediating effect of psychological distress and wellbeing in the association between anti-mattering and irritability among a sample of Lebanese adolescents-a topic that remains largely underexplored in adolescent mental health research.

methodsA cross-sectional study was conducted during November 2023 and included 763 adolescents currently residing in Lebanon (mean age 16.08 ± 1.74 years, 37.6% males and 62.4% females) recruited from all Lebanese governorates using a snowball sampling technique. Data were collected via an online questionnaire and analyzed using the PROCESS Macro for mediation analysis.

resultsThe findings indicated that both psychological distress (β = .39, BootSE = .04, 95% CI [.33,.46]) and wellbeing (β = .07, BootSE = .02, 95% CI [.03,.12]) partially mediated the relationship between anti-mattering and irritability. Adolescents with higher levels of anti-mattering reported greater distress and reduced wellbeing, both of which were associated with increased irritability.

conclusionOur results highlight the psychological relevance of anti-mattering in adolescence and suggest that addressing feelings of insignificance may play a key role in managing emotional dysregulation. Mental health practitioners and educators should consider developing culturally sensitive interventions that target feelings of anti-mattering, enhance wellbeing, and reduce psychological distress. School-based programs promoting emotional support and social inclusion may prove especially beneficial. Future studies should investigate these associations longitudinally and across varied cultural contexts to better inform prevention and intervention strategies.

Indexed as

Irritable MoodPsychological DistressStress, PsychologicalAdolescentCross-Sectional StudiesFemaleHumansLebanonMaleMental HealthSurveys and Questionnaires

Identifiers

PMID41086242
PMCPMC12520367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.