Evidence map›Paper›PMID 41086220›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Spontaneous activity of astrocytes is a stochastic functional signal for memory consolidation.

Gabriele Losi, Beatrice Vignoli, Rocco Granata, Annamaria Lia, Micaela Zonta, Gabriele Sansevero, Francesca Pischedda, Angela Chiavegato, Spartaco Santi, Lorena Zentilin and 4 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Astrocyte CaBiomolecules · 2026
    Review
  4. Mitochondrial CaBiomolecules · 2026
    Review
  5. Review
  6. Spontaneous activity of astrocytes is a stochastic functional signal for memory consolidation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gabriele Losi *Institute of Neuroscience, National Research Council, Padova section, Padova 35131, Italy.ORCID 0000-0002-4931-6167
Beatrice Vignoli *Institute of Neuroscience, National Research Council, Padova section, Padova 35131, Italy.
Rocco GranataCenter for Nanotechnology Innovation (NEST- National Enterprise for nanoScience and nanoTechnology), Scuola Normale Superiore, Pisa 56126, Italy.
Annamaria LiaDepartment of Biomedical Sciences, University of Padova, Padova 35131, Italy.ORCID 0000-0001-5465-9941
Micaela ZontaInstitute of Neuroscience, National Research Council, Padova section, Padova 35131, Italy.ORCID 0000-0002-9982-6405
Gabriele SanseveroInstitute of Neuroscience, National Research Council, Pisa section, Pisa 56125, Italy.ORCID 0000-0003-0562-5459
Francesca PischeddaDepartment of Physics, University of Trento, Povo (TN) 38123, Italy.ORCID 0000-0003-2006-2607
Angela ChiavegatoInstitute of Neuroscience, National Research Council, Padova section, Padova 35131, Italy.ORCID 0000-0002-9583-4707
Spartaco SantiInstitute of Molecular Genetics "Luigi Luca Cavalli-Sforza," National Research Council, Bologna 40100, Italy.ORCID 0000-0001-9856-7053
Lorena ZentilinInternational Centre for Genetic Engineering and Biotechnology, Padriciano (TS) 34149, Italy.ORCID 0000-0001-7514-8155
Nicoletta BerardiInstitute of Neuroscience, National Research Council, Pisa section, Pisa 56125, Italy.
Gian Michele RattoCenter for Nanotechnology Innovation (NEST- National Enterprise for nanoScience and nanoTechnology), Scuola Normale Superiore, Pisa 56126, Italy.ORCID 0000-0001-9632-7769
Giorgio Carmignoto *Institute of Neuroscience, National Research Council, Padova section, Padova 35131, Italy.ORCID 0000-0003-3063-6774
Marco Canossa *Department of Cellular Computational and Integrative Biology, University of Trento, Povo (TN) 38123, Italy.

Funding

Consiglio Nazionale delle Ricerche (CNR) Premiale TERRABIO 2017EC | European Research Council (ERC) 788793-BACKUPMinistero dell'Istruzione, dell'Università e della Ricerca (MIUR) 2015W2N883_001Ministero dell'Istruzione, dell'Università e della Ricerca (MIUR) 2017HPTFFCPRINMinistero dell'Istruzione, dell'Università e della Ricerca (MIUR) Premiale Nano4BrainMinistero dell'Università e della Ricerca (MUR) 20175C22WMMinistero dell'Università e della Ricerca (MUR) #NEXTGENERATIONEU (NGEU); the Ministry of University and Research (MUR); the National Recovery and R
6 · The paper itself

Abstract

In the absence of explicit neuronal inputs, the glial cell astrocytes exhibit recurring intracellular Ca

Indexed as

AstrocytesMemoryMemory ConsolidationAnimalsBrain-Derived Neurotrophic FactorCalciumCalcium SignalingLong-Term PotentiationMaleMiceMice, Inbred C57BLReceptor, trkBSignal TransductionStochastic ProcessesBrain-Derived Neurotrophic FactorCalciumReceptor, trkBCa2+ microdomainsmemory circuitsneurotrophinssynaptic plasticity

Identifiers

PMID41086220
PMCPMC12557542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.