ArticlePloS one2025
Ovariole number does not predict reproductive output or trade-off with immunity in Drosophila melanogaster.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
Reproduction and immunity are two energetically demanding traits that frequently trade-off with each other. Prior studies have suggested that the cost of reproduction limits the ability of Drosophila melanogaster females to fight bacterial infections, including the direct cost of developing and provisioning eggs. Ovariole number is a genetically variable trait in Drosophila, and is frequently assumed to be a good indicator of reproductive capacity. This implies ovariole number might also predict the quality of defense against bacterial infection. Here, we used 13 isogenic lines from the Drosophila Genomic Reference Panel to test whether reproductive investment trades off with immune response. These lines vary genetically for ovariole number, but we found ovariole number is not a predictor of reproductive output in infected females nor of resistance to bacterial infection. Furthermore, we saw no strong genetic tradeoff between fecundity and defense against infection in our experimental framework. Our results suggest that the evolutionary trade-off between reproduction and immunity could be weak, at least when measured in the laboratory, even when the physiological trade-off between these two traits is strong.
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