Evidence map›Paper›PMID 41085946›Full record

ArticleEJNMMI physics2025

Optimal image-derived input function models for multi-parameter analysis and acceptably reduced acquisition time in [

Jiahao Xie, Dazhi Shi, Ganghua Tang, Lijuan Wang, Yanchao Huang, Kemin Zhou, Ying Tian, Penghui Sun, Yanjiang Han, Hubing Wu

Abstract read
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiahao Xie *Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Dazhi Shi *Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Ganghua Tang *Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Lijuan WangDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Yanchao HuangDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Kemin ZhouDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Ying TianDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Penghui SunDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China.
Yanjiang HanDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China. riverhanyj@163.com.
Hubing WuDepartment of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou North Road, Guangzhou, China. wuhbym@163.com.ORCID http://orcid.org/0000-0002-7546-5430

Funding

Basic and Applied Basic Research Foundation of Guangdong Province No. 2021A1515111230Guangzhou Key Research and Development Program on Agriculture and Social Development Science 2024B03J0631, SL2023B03J00187National Natural Science Foundation of China No.82171984National Natural Science Foundation of China No.82371995National Natural Science Foundation of China No.82402326
6 · The paper itself

Abstract

purposeLung tumors, which receive dual-blood-supply from the pulmonary and bronchial arteries, may exhibit distinct kinetic parameters compared to other malignancies. This study aimed to investigate the impact of various factors on the kinetic parameter quantification of [

methodsA total of 19 patients with lung tumors underwent 60-minute total-body dynamic [

resultsThe time-activity curve (TAC) of the RV exhibited the earliest and highest peak, followed by those of the LV and DA. Impact of IDIF model and tumor size on kinetic parameters of primary tumors was observed. Specifically, in the RVIF model, size of tumor > 3 cm exhibited higher K

conclusionThe RVIF model appears to be more suitable than the DAIF model for quantifying kinetic parameters in [

Indexed as

[18F]F-FAPI-42Arterial input functionsDynamic imagingShort-time imagingTotal-body PET/CT

Identifiers

PMID41085946
PMCPMC12521698

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.