Evidence map›Paper›PMID 41085900›Full record

ArticleVeterinary research communications2025

Metabolic and cardiovascular effects of obesity in domestic cats.

Thais Alessandra Dos Santos, Aline Gomes Rosa, Brenda da Silva, Jucemara Madel de Medeiros, Leonardo Deschamps Fernandes, Alex Sandro Uliana, Mere Erika Saito, Leticia Andreza Yonezawa

Abstract read
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In one paragraph

Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thais Alessandra Dos SantosCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil. thaisalesantos@gmail.com.ORCID http://orcid.org/0000-0003-2017-2929
Aline Gomes RosaCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0009-0003-5361-5682
Brenda da SilvaCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0002-2166-8072
Jucemara Madel de MedeirosCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0003-1753-2743
Leonardo Deschamps FernandesCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0001-8310-9594
Alex Sandro UlianaCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0001-5974-0730
Mere Erika SaitoCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0002-1232-4657
Leticia Andreza YonezawaCentro de Ciências Agroveterinárias (CAV), Universidade do Estado de Santa Catarina (UDESC) - Lages, Lages, SC, Brasil.ORCID http://orcid.org/0000-0002-1506-9620

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.902202/2023-00Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina , Brasil 2023TR000513
6 · The paper itself

Abstract

Obesity in cats has become increasingly prevalent in clinical practice and is associated with several comorbidities and reduced longevity. However, data on metabolic alterations in overweight or obese cats remain limited. This study aimed to evaluate hematological, lipid profile, oxidative metabolism, and cardiovascular parameters in overweight and obese cats. A total of 42 neutered mixed-breed cats were included and divided into three groups (n = 14): control group, overweight group, and obese group. Animals were selected based on medical history, physical examination, complete blood count, FIV/FeLV serology, and biochemical profile; individuals with comorbidities were excluded. Evaluations included complete blood count, lipid profile, malondialdehyde (MDA), reduced glutathione (GSH), erythrocyte osmotic fragility, electrocardiogram, and systemic blood pressure. Overweight cats showed significantly elevated cholesterol levels (179.93 ± 37.41 mg/dL; p = 0.003). Obese cats showed lymphopenia (1175 cells/µL; 871-2662), increased cholesterol (181.92 ± 27.78 mg/dL; p = 0.003), triglycerides (117 mg/dL; 80-211; p = 0.002), very low-density lipoprotein (VLDL) (30.7 ± 20 mg/dL; p = 0.001), and systolic blood pressure (160.3 ± 20.56 mmHg; p < 0.001) compared to the control group. In conclusion, feline obesity induces significant alterations in hematological, lipid, and cardiovascular parameters, indicating a relevant systemic impact.

Indexed as

Cardiovascular DiseasesCat DiseasesObesityAnimalsBlood PressureCatsFemaleLipidsMaleLipidsDyslipidemiasFelineOverweightOxidative metabolismSystemic blood pressure

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.