ArticleIndian journal of pediatrics2025
Genotype Distribution of Rotavirus Strains and Its Association with Severity of Diarrhea Among Children Under Five Hospitalized with Acute Gastroenteritis in Odisha, India.
Article in Indian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
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Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivesGlobally, diarrheal diseases are a leading cause of infectious disease morbidity and mortality among children aged under 5 y. Rotavirus is a primary cause of severe diarrhea in children, and India accounts for 22% of rotavirus deaths worldwide. This study aimed to determine the prevalence and distribution of circulating rotavirus genotypes among hospitalized children aged under 5 y in Odisha, India.
methodsThis prospective hospital-based study was conducted between January and December 2023 at four tertiary care hospitals in Odisha. Stool samples were collected from enrolled children aged under 5 y admitted with acute gastroenteritis and tested for rotavirus antigen at a central laboratory using an enzyme-linked immunosorbent assay (ELISA). The ELISA-positive samples were genotyped using heminested reverse-transcription polymerase chain reaction.
resultsOf the 365 children enrolled, 288 had their stool samples tested for rotavirus. Rotavirus was confirmed in 67 (23.3%) children, and 66 samples were genotyped. The most prevalent genotypes were G2P[4] (n = 27, 40.9%) and G3P[8] (n = 22, 33.3%).
conclusionsThese findings highlight the importance of ongoing molecular surveillance to monitor the circulating rotavirus strains to inform public health strategies and future research aimed at optimizing rotavirus vaccination programs.
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