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ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2026

TF-TAVI and SAVR post-procedural complications in Germany 2021/2022 - impact on healthcare resource consumption.

Alexander Maier, Alicja Zientara, Markus Jäckel, Jonathan Rilinger, Christian Weber, Vera Oettinger, Lukas A Heger, Derek Hazard, Roman Gottardi, Martin Czerny and 3 more

Abstract read
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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Alexander MaierDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany. alexander.maier@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0003-0200-7495
Alicja ZientaraDepartment of Cardiovascular Surgery, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Markus JäckelDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Jonathan RilingerDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christian WeberDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Vera OettingerDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Lukas A HegerDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Derek HazardInstitute of Medical Biometry and Statistics, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Roman GottardiDepartment of Cardiovascular Surgery, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Martin CzernyDepartment of Cardiovascular Surgery, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Dirk WestermannDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Constantin von Zur MühlenDepartment of Cardiology and Angiology, University Heart Center Freiburg - Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Klaus KaierInstitute of Medical Biometry and Statistics, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-procedural complications after transfemoral transcatheter aortic valve implantation (TF-TAVI) lead to extended healthcare resource consumption. A comparison with resource consumption after surgical aortic stenosis valve replacement (SAVR) complications has not been conducted.

methodsThe impact of acute kidney injury (AKI), stroke, severe bleeding and permanent pacemaker implantation (PPI) on length of stay, mechanical ventilation > 48 h and reimbursement was analyzed by risk-adjusted linear and logistic regression analyses of all German aortic stenosis TF-TAVI and SAVR cases 2021/2022.

results48,565 TF-TAVI and 9,803 SAVR procedures for aortic stenosis treatment were performed in Germany 2021/2022. The length of stay for TF-TAVI was shorter (10.16 ± 7.19 vs. 13.91 ± 9.82 days, p < 0.001), the rate of mechanical ventilation > 48 h was lower after TF-TAVI (1.3% vs. 7.0%, p < 0.001) and reimbursement was higher for TF-TAVI (26,483 ± 4,487 vs. 20,538 ± 11,748 €, p < 0.001). Length of stay was increased by all investigated complications after TF-TAVI and SAVR (p < 0.001) with the highest increase after bleeding in TF-TAVI. Odds ratios for mechanical ventilation > 48 h were significantly increased for stroke, severe bleeding and AKI (p < 0.001) but not for PPI after both TF-TAVI and SAVR with the highest OR increase after bleeding in TF-TAVI. Reimbursement was significantly increased after TF-TAVI and SAVR by all investigated complications (p < 0.001) finding significantly higher increases after SAVR compared to TF-TAVI for all complications. The total hospital stay after stroke, AKI and PPM was longer for SAVR (p < 0.001), while severe bleeding led to longer total hospital stay after TF-TAVI (p < 0.001). Total reimbursement remained higher for TF-TAVI after all investigated complications (p < 0.001).

conclusionHealthcare resource consumption differs between TF-TAVI and SAVR for aortic stenosis treatment also after procedural complications. SAVR is associated with longer hospitalization and more mechanical ventilation, while TF-TAVI is associated with higher reimbursement in the German healthcare system. Complications lead to increased resource use for both procedures with higher extra reimbursement for SAVR and more extra hospital days for TF-TAVI after bleeding reversing the length of stay advantage.

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationPostoperative ComplicationsTranscatheter Aortic Valve ReplacementAcute Kidney InjuryAgedAged, 80 and overFemaleGermanyHumansLength of StayMaleRespiration, ArtificialComplicationsHealthcare resourcesSAVRTAVI

Identifiers

PMID41085855
PMCPMC13190498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.