Evidence map›Paper›PMID 41085841›Full record

ArticleWorld journal of microbiology & biotechnology2025

Bacillus paralicheniformis strain H12 from saline soil for the management of gray mold in cherry tomatoes.

Amina Ghozlani, Fatma Driss, Duong Huy Nguyen, Hanane Boumerdassi, Fairouz El Aichar, Lydia Neïla Djouadi, Pedro H Oliveira, Marie-Laure Fardeau, Nathalie Pradel, Souad Rouis and 2 more

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Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amina GhozlaniMicrobiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology - Houari Boumediene, Algiers, Bab Ezzouar, 16111, Algeria.
Fatma Driss *Laboratory of Biopesticides, Centre of Biotechnology of Sfax, University of Sfax, P.O. Box 1177, Sfax, 3018, Tunisia.
Duong Huy Nguyen *Institute of Biology (IB), Vietnam Academy of Science and Technology (VAST), Hanoi, 10072, Vietnam.
Hanane BoumerdassiMicrobiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology - Houari Boumediene, Algiers, Bab Ezzouar, 16111, Algeria.
Fairouz El AicharMicrobiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology - Houari Boumediene, Algiers, Bab Ezzouar, 16111, Algeria.
Lydia Neïla DjouadiMicrobiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology - Houari Boumediene, Algiers, Bab Ezzouar, 16111, Algeria.
Pedro H OliveiraCommissariat à l'Energie Atomique (CEA), Génomique Métabolique, Institut François Jacob, CNRS, Université Evry, Université Paris-Saclay, Genoscope, France.
Marie-Laure FardeauAix Marseille Univ, Université de Toulon, CNRS, IRD, MIO, Marseille, France.
Nathalie PradelAix Marseille Univ, Université de Toulon, CNRS, IRD, MIO, Marseille, France.
Souad RouisLaboratory of Biopesticides, Centre of Biotechnology of Sfax, University of Sfax, P.O. Box 1177, Sfax, 3018, Tunisia.
Olfa Frikha-GargouriLaboratory of Biopesticides, Centre of Biotechnology of Sfax, University of Sfax, P.O. Box 1177, Sfax, 3018, Tunisia.
Farida NatecheMicrobiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology - Houari Boumediene, Algiers, Bab Ezzouar, 16111, Algeria. fnateche@usthb.dz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal phytopathogens cause severe yield loss, endangering vital crops such as cherry tomatoes. This study was undertaken to investigate and identify Bacillus species that possess broad-spectrum antifungal activity, specifically, to select a biocontrol agent against gray mold disease caused by Botrytis cinerea affecting cherry tomato, and investigating its safety features (antibiotic resistance, hemolysis, and virulence genes). Out of 82 Bacillus strains isolated from different regions in Algeria, 41 strains exhibited antifungal activity, while 28 strains demonstrated broad-spectrum activity. In vitro studies showed that each isolate produced at least one lytic enzyme (chitinase, glucanase, amylase, protease, or lipase). The most promising strains were all classified within the Bacillus subtilis group based on 16 S rRNA sequencing. The biocontrol potential of B. paralicheniformis H12 strain, which exhibited the highest inhibition index against B. cinerea, was tested in vivo. The assays showed that H12 strain significantly decreased the gray mold decay in cherry tomatoes and resulted in less weight loss (weight loss rate 2.76%) compared to the control group (5.04%). The genome of H12 consisted of 4,283,563 bp, with 4,226 coding DNA sequences, and a GC content of 45.87%. Genome mining unveiled diverse biosynthetic gene clusters related to antimicrobial properties. Furthermore, H12 was categorized as non-hemolytic and sensitive to different antibiotic families. These findings highlight the potential of B. subtilis group species as a potential biocontrol agent. Specifically, they provide valuable insight into the genomic features of the B. paralicheniformis strain H12 from saline soil (sabkha) as a prospective candidate for agricultural application.

Indexed as

BacillusBotrytisPlant DiseasesSoil MicrobiologySolanum lycopersicumAlgeriaAntifungal AgentsBiological Control AgentsGenome, BacterialPhylogenyRNA, Ribosomal, 16SSoilAntifungal AgentsBiological Control AgentsRNA, Ribosomal, 16SSoilBacillus subtilis groupBiocontrol agentBroad-spectrum antifungal activityWhole-genome sequencing

Identifiers

PMID41085841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.