Evidence map›Paper›PMID 41085840›Full record

ArticleJournal of materials science. Materials in medicine2025

Bioactivity and biocompatibility of bioceramic-based pulp capping materials in laboratory and animal models.

Rafiqul Islam, Md Refat Readul Islam, Kenta Tsuchiya, Yu Toida, Hidehiko Sano, Monica Yamauti, Hany Mohamed Aly Ahmed, Atsushi Tomokiyo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafiqul IslamDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan. rony12cdc@den.hokudai.ac.jp.ORCID http://orcid.org/0000-0002-1409-8112
Md Refat Readul IslamDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.
Kenta TsuchiyaDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.
Yu ToidaDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.
Hidehiko SanoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.
Monica YamautiDepartment of Biomedical and Applied Science, School of Dentistry, Indiana University, Indianapolis, IN, USA.
Hany Mohamed Aly AhmedDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur, Malaysia.
Atsushi TomokiyoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.

Funding

Japan Society for the Promotion of Science JP24K12924
6 · The paper itself

Abstract

Recently, premix bioceramic-based pulp capping (BPC) materials have been introduced with desirable properties. However, data regarding the bioactivity and biocompatibility of these materials remain limited. This present study aimed to evaluate the bioactivity and biocompatibility of BPC materials. This study consisted of five experimental groups: Bio C Repair (BCR); BG Multi (BGM); Well pulp ST (WPS); ProRoot MTA (PMTA); and a no capping (NC) group. Measurement of pH, calcium ion (Ca

Indexed as

Biocompatible MaterialsCeramicsDental Pulp CappingPulp Capping and Pulpectomy AgentsAnimalsCalciumCalcium CompoundsDental PulpHydrogen-Ion ConcentrationMaleMaterials TestingModels, AnimalNestinOsteopontinRatsRats, WistarBiocompatible MaterialsCalciumCalcium CompoundsNestinOsteopontinPulp Capping and Pulpectomy AgentsSilicatesBioactivityBioceramic materialBiocompatibilityDirect pulp cappingMineral trioxide aggregate

Identifiers

PMID41085840
PMCPMC12521281

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.