ArticleDiscover oncology2025
Endoscopic therapy versus surgical resection for rectal gastrointestinal stromal tumors: a population-based comparative analysis of long-term survival outcomes.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Case Report and Literature Review of a Rectal Gastrointestinal Stromal Tumor.ACG case reports journal · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRectal gastrointestinal stromal tumors (GISTs) are relatively rare, and the long-term survival outcomes of endoscopic therapy (ET) versus surgical resection (SR) remain uncertain. This study aims to assess the long-term survival in patients with rectal GISTs treated with either ET or SR.
methodsPatients were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Propensity score matching (PSM) was implemented to reduce selection bias in the comparative analyses. The impact of demographic and clinical features on overall survival (OS) and cancer-specific survival (CSS) was evaluated through Kaplan-Meier analyses and the use of multivariate Cox proportional hazards models.
resultsA total of 239 patients were included, with 146 undergoing ET and 93 undergoing SR. After PSM, 164 patients were evenly matched for comparison. There was no significant distinction between ET and SR regarding long-term OS (P = 0.592) and CSS (P = 0.832). Furthermore, subgroup analysis considering factors like age, tumor size, year of diagnosis, and sex also found no variance in OS and CSS outcomes between the groups. The multivariate Cox analysis identified advanced age as the sole independent risk factor impacting the prognosis of patients with rectal GISTs.
conclusionsOur findings suggest that ET and SR offer comparable long-term survival outcomes for patients with rectal GISTs, indicating that ET could be considered a viable treatment option.
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