ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Association of supportive care team intervention with nutritional status, adverse events, and treatment status in patients with head and neck cancer undergoing concurrent chemoradiotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeAt the National Hospital Organization Kumamoto Medical Center, the supportive care team (SCT) provides supportive care to all patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). This study aimed to investigate the relationship between SCT intervention and the nutritional status, adverse events, and treatment status of patients with HNC undergoing CCRT.
methodsThis study enrolled 40 patients with HNC who underwent CCRT. The primary endpoint was the body weight (BW) loss rate. The secondary endpoints were energy intake, incidence of adverse events, and treatment completion rate.
resultsBW loss rate (9.0 ± 5.0 vs. 5.5 ± 3.4%; p = 0.017) was significantly lower in the SCT intervention group (n = 20) than in the non-SCT intervention group (n = 20). The energy intake of radiation therapy (RT) 22-40 Gy (21.0 ± 6.9 vs. 25.4 ± 4.6 kcal/kg ideal BW [IBW]; p = 0.024) and RT 42-60 Gy (22.6 ± 7.2 vs. 26.3 ± 3.8 kcal/kg IBW; p = 0.048) were significantly higher in the SCT intervention group than in the non-SCT intervention group. The incidence of grade 3 or higher oral mucositis was significantly lower in the SCT intervention group than in the non-SCT intervention group (40.0 vs. 10.0%; p = 0.028). The completion rate of CCRT was significantly higher in the SCT intervention group than in the non-SCT intervention group (55.0 vs. 85.0%; p = 0.038).
conclusionSCT intervention in patients with HNC undergoing CCRT was associated with reduced BW loss rate.
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