Evidence map›Paper›PMID 41085730›Full record

SynthesisNeurosurgical review2025

Liquid vs. solid: The superior choice of material in intracranial tumors preoperative embolization - A systematic review and meta-analysis.

Yuhang Zhao, Minghao Han, Tianhe Cai, Suli Liu, Cheng Fu, Wentao Li, Longyi Zhou, Jie Ding, Yi Zhang

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuhang ZhaoCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Minghao HanCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Tianhe CaiNanjing Medical University, Jiangsu Province, Nanjing, People's Republic of China.
Suli LiuCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Cheng FuCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Wentao LiCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Longyi ZhouCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China.
Jie DingDepartment of Biochemistry and Molecular Biology, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China. dingjie711@seu.edu.cn.
Yi ZhangCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Cultivation and Construction Site of the State Key Laboratory of Intelligent Imaging and Interventional Medicine, Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, Jiangsu Province, Nanjing, People's Republic of China. yizhangcir@126.com.

Funding

National Key Research and Development Program of China 2024YFB4708804Science and Technology Support Program of Jiangsu Province BE2023769
6 · The paper itself

Abstract

objectiveTo compare the impacts of solid versus liquid​ embolization materials during preoperative embolization of intracranial tumors.

methodsRelevant articles from January 1975 to September 2024 were included. Meta-analysis focused on average operation duration and estimated blood loss. Heterogeneity was also evaluated.

resultsA total of 7 retrospective studies were included, in which a total of 361 patients met the criteria and were thus included. There were 220 female patients, accounting for 60.9%. The patients were divided into the liquid embolization group and the solid embolization group. We discovered that during the preoperative embolization of intracranial tumors, the selection of liquid versus solid materials did not significantly influence the estimated blood loss (MD = -98.5; 95% confidence interval [CI] - 290 ~ 93). Additionally, in terms of the impact on surgical operation duration, no significant statistical difference was observed between the two groups either (MD = 5.6; 95% confidence interval [CI] - 55 ~ 43).

conclusionThe current meta-analysis reveals that, in patients undergoing preoperative embolization of intracranial tumors, there is no significant statistical difference in operation duration and estimated blood loss in the surgical resection of intracranial tumors among different preoperative embolization materials during subsequent tumor resection procedures. ​Material selection should be individualized​ based on tumor characteristics and operator expertise.

Indexed as

Brain NeoplasmsEmbolization, TherapeuticPreoperative CareBlood Loss, SurgicalHumansNeurosurgical ProceduresEmbolization materialIntracranial tumorsPreoperative

Identifiers

PMID41085730
PMCPMC12521332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.