ArticleArchives of orthopaedic and trauma surgery2025
Inflammatory bowel disease and its association with increased PJI risk in total hip arthroplasty: the role of steroid use.
Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- After total hip arthroplasty, patients with glucocorticoid-treated osteonecrosis of the femoral head have a higher risk of in-hospital reoperation: a nationwide propensity score-matched analysis.International orthopaedics · 2026Article
- Chronic Corticosteroid Use Is Associated with Higher Perioperative Morbidity After Elective Primary Total Hip Arthroplasty.Journal of clinical medicine · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
introductionThis study investigated the association between medication status and total hip arthroplasty (THA) complications in patients with inflammatory bowel disease (IBD), considering varying illness severities. MATERIALS AND
methodsThis retrospective analysis of the National Health Insurance Review and Assessment Service database in South Korea, included patients undergoing unilateral THA between 2012 and 2022, specifically those diagnosed with IBD. Propensity score matching was used to adjust for baseline characteristics between IBD and non-IBD cohorts, with a matching ratio of 1:10.
resultsThere was a significant difference between the IBD (n = 962) and non-IBD matched groups (n = 9,620) in terms of chronic periprosthetic joint infection (PJI) (2.1 vs. 1.3%, P= 0.03) but not with acute PJI or other surgical complications (periprosthetic fracture, dislocation, and aseptic loosening). While medication use overall was not associated with PJI, only corticosteroid use among IBD medications was significantly associated with PJI among IBD medications (OR: 2.79 [1.03-10.68], P = 0.04). Specifically, multivariable analysis revealed that corticosteroid use within one year before THA was associated with a significant increase in PJI risk (OR: 3.30 [1.21-10.86], P = 0.02). Patients with IBD who were not using steroids did not show an increased risk of PJI.
conclusionsWhile IBD increased the risk of chronic PJI, the risk was remarkable in patients using steroids, particularly in the context of poorly controlled IBD and acute flares-up. Preoperative steroid use within one year before THA conferred the greatest risk. Attention should be directed towards recognizing the risk of steroid use before THA. LEVEL OF EVIDENCE: Level III, Prognostic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.