Evidence map›Paper›PMID 41085615›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2026

Introduction to the Immune System.

Scott McComb, Aude Thiriot, Bassel Akache, Lakshmi Krishnan, Felicity C Stark

Abstract readReview
PubMed Publisher
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Scott McCombHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Aude ThiriotHarvard University, Boston, MA, USA.
Bassel AkacheHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Lakshmi KrishnanHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
Felicity C StarkHuman Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada. Felicity.Stark@nrc-cnrc.gc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system in a broad sense is a mechanism that allows a living organism to discriminate between "self" and "non-self." Examples of immune systems occur in multicellular organisms as simple and ancient as sea sponges. In fact, complex multicellular life would be impossible without the ability to exclude external life from the internal environment. This introduction to the immune system will explore the cell types and soluble factors involved in immune reactions, as well as their location in the body during development and maintenance. Additionally, a description of the immunological events during an innate and adaptive immune reaction to an infection will be discussed, as well as a brief introduction to autoimmunity and cancer immunity.

Indexed as

Immune SystemAdaptive ImmunityAnimalsAutoimmunityHumansImmunity, InnateNeoplasmsAdaptive immunityAdjuvantsCAR-TCheckpointImmune systemImmunityInflammationInnate immunityVaccines

Identifiers

PMID41085615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.