Evidence map›Paper›PMID 41085524›Full record

SynthesisAnnals of medicine2025

Added value of 3'-deoxy-3'-[

Bandar Alwadani, Louy Nammazi, Osama Suwaydi, Ziyad Faqih, Abdullah Agily, Omar Abdali, Mozdalifah Elnaeem, Ali S Alyami, Yahia Madkhali, Wael Ageeli and 2 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bandar AlwadaniDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.ORCID 0000-0001-8951-630X
Louy NammaziDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Osama SuwaydiDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Ziyad FaqihDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Abdullah AgilyDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Omar AbdaliKing Abdulaziz Hospital, Jeddah, Saudi Arabia.
Mozdalifah ElnaeemDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Ali S AlyamiDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.ORCID 0000-0001-5774-5466
Yahia MadkhaliDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Wael AgeeliDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.ORCID 0000-0001-9716-0438
Turkey RefaeeDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Naif MajrashiDiagnostic Radiography Technology (DRT) Department, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCurrent tools for evaluating therapy response in head and neck cancer (HNC) have multiple limitations, such as poor representation of heterogeneous tumours, potential complications associated with biopsy collection, and late anti-cancer effects on tumour, leading to delayed evaluation. Therefore, an accurate tool that can assess early therapy response in HNC patients is urgently needed. Positron emission tomography using 3'-deoxy-3'-[ MATERIALS AND

methodsMedline and Embase databases via Ovid interface were searched on the basis of the search strategy and selection criteria. Evidence linking the tumour uptake of [

resultsUltimately, eight studies comprising 225 patients showed significant reduction of [

conclusions[

Indexed as

DideoxynucleosidesHead and Neck NeoplasmsPositron-Emission TomographyHumansRadiopharmaceuticalsTreatment OutcomealovudineDideoxynucleosidesRadiopharmaceuticals[18F]FLTcell proliferationhead and neck cancerimaging biomarkerpositron emission tomographytherapy response

Identifiers

PMID41085524
PMCPMC12523450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.