Evidence map›Paper›PMID 41085261›Full record

ArticleFuture microbiology2025

Trajectory and trends in molecular regulation of

Yi Yin, Sishi Dong, Xinze Wu, Xiangyi Zhao, Yudi Deng, Yufei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi YinState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Sishi DongState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Xinze WuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Xiangyi ZhaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Yudi DengState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Yufei WangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsDental caries is a globally chronic disease, with METHODS &

methodsThis study conducted a comprehensive bibliometric and scientometric analysis of 470 publications from 1994 to 2024 using Web of Science Core Collection data. Advanced analytical platforms, including CiteSpace, VOSviewer and R, were employed to visualize the field's development trajectories and identify hotspots.

resultsThe results reveal an evolving focus from basic gene-level and metabolic studies to complex regulatory networks involving quorum sensing, two-component systems and environmental adaptation. In recent years, increasing emphasis has been placed on post-transcriptional and post-translational regulatory mechanisms, notably lysine acetylation, malonylation, and glutathionylation, which orchestrate virulence factor expression, stress responses, and biofilm dynamics.

conclusionsThis work provides the first systematic overview of the development, hotspots, and emerging trends in molecular regulation of

Indexed as

Dental CariesGene Expression Regulation, BacterialStreptococcus mutansBacterial ProteinsBibliometricsBiofilmsHumansQuorum SensingVirulenceVirulence FactorsBacterial ProteinsVirulence FactorsBibliometric analysisCiteSpacedental carieshotspotspost-translational modificationsStreptococcus mutanstrends

Identifiers

PMID41085261
PMCPMC12667637

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.