ArticleJournal of the American Heart Association2025
Risk Factors for Reintervention Following Treatment for Aortic Coarctation With or Without Aortic Arch Hypoplasia in Sweden: From Isolated Coarctation to Complex Bi- and Univentricular Congenital Heart Disease.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Hybrid aortic arch repair for recoarctation and arch aneurysm with concomitant multivalvular surgery.JTCVS structural and endovascular · 2026Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundRepaired coarctation of the aorta (CoA)-either simple or as part of complex congenital heart disease-can be associated with long-term sequelae such as recoarctation of the aorta (reCoA) or arterial hypertension. The aim of this study was to determine the prevalence and risk factors for requiring reintervention for reCoA in patients with simple as well as complex bi- and univentricular types of congenital heart disease.
methodsData on patients with a diagnosis of CoA were retrieved from the SWEDCON (Swedish National Registry of Congenital Heart Disease) from 1973 to 2020. Surgically and catheter-based repaired CoA were analyzed separately.
resultsThe study included 1609 children and adults with surgically repaired CoA and 170 with catheter-based CoA intervention. A total of 249 (15%) of the patients after surgically repaired CoA and 59 (35%) after catheter-based repaired CoA received interventions for reCoA. The risk of aortic reintervention following primary surgical CoA repair was increased in patients with complex biventricular and univentricular congenital heart disease. Use of patch augmentation and aortic arch reconstruction through Norwood procedure were associated with increased risk of reCoA, whereas end-to-end or end-to-side anastomosis were associated with a decreased risk of reCoA. Younger age at primary surgical CoA repair was associated with increased risk of reCoA. Overall, a high prevalence of hypertension was observed.
conclusionsOur study shows for the first time that patients with univentricular and biventricular complex CHD and those following patch aortoplasty or single ventricle palliation with Norwood surgery are at a higher risk for reintervention at the CoA site after surgical repair than patients with uncomplicated CoA.
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