Evidence map›Paper›PMID 41084973›Full record

ReviewCell cycle (Georgetown, Tex.)

Enigmatic functions of ATP8B1: cholestasis, inflammation, phosphoinositide flipping, and cellular homeostasis.

Ashutosh Prince, C Alicia Traughber, Yavar Shiravand, Nilam Bhandari, Mariam R Khan, Swati Sharma, Kara Timinski, Karen F Murray, Laura N Bull, Kailash Gulshan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell cycle (Georgetown, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashutosh PrinceCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
C Alicia TraughberCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Yavar ShiravandCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Nilam BhandariCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Mariam R KhanCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Swati SharmaCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Kara TiminskiCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.
Karen F MurrayDepartment of Pediatrics, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Laura N BullInstitute for Human Genetics and Liver Center Laboratory, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Kailash GulshanCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH, USA.ORCID 0000-0002-5598-7370

Funding

Phosphatidylinositol Metabolism and Trafficking in Atherosclerosis and InflammationR01HL148158 · NHLBI · CLEVELAND STATE UNIVERSITY · PI Kailash Gulshan · 2020 to 2026
$3.1M
NHLBI NIH HHS R01 HL148158
6 · The paper itself

Abstract

Mutations in

Indexed as

Adenosine TriphosphatasesCholestasisCholestasis, IntrahepaticHomeostasisInflammationPhosphatidylinositolsAnimalsHumansAdenosine TriphosphatasesATP8B1 protein, humanPhosphatidylinositolsATP8B1efferocytosisGasdermin D (GSDMD)interleukin 1 beta (IL-1β)PFIC1PIP2

Identifiers

PMID41084973
PMCPMC12918318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.