SynthesisBirth defects research2025
Electrostimulation in Children With Neurogenic Bladder due to Spina Bifida: Systematic Review and Meta-Analysis.
Synthesis in Birth defects research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Electrostimulation in Children With Neurogenic Bladder due to Spina Bifida: Systematic Review and Meta-Analysis.Birth defects research · 2025Pooled it
- Electrical and Functional Magnetic Stimulation in the Management of Children's Lower Urinary Tract Dysfunction-A Current Literature Review.Children (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis systematic review and meta-analysis aimed to evaluate the efficacy of electrotherapy techniques in the treatment of neurogenic bladder in children with spina bifida.
methodsA systematic search was conducted in MEDLINE, EMBASE, Web of Science, PEDro, and Biblioteca Virtual databases for studies published up to February 2025. Eligible studies included children aged 3-21 with neurogenic bladder due to spina bifida who underwent invasive or non-invasive electrotherapy. The outcomes included were bladder compliance, while secondary outcomes assessed cystometric capacity, detrusor pressure, detrusor leak point pressure, and lower urinary tract symptoms. Methodological quality was assessed using the PEDro scale and the Cochrane Risk of Bias Tool for randomized studies, and the ROBINS-I tool for non-randomized studies. This study was prospectively registered in the Prospero database (CRD-42021242845).
results9 studies involving 303 participants (180 receiving electrotherapy and 123 controls) were included, of which four were eligible for meta-analysis. Electrotherapy showed a moderate increase in bladder compliance (+2 mL/cmH2O, 95% CI: 0-5) and maximum cystometric capacity (+73 mL, 95% CI: 56-90). Detrusor pressure decreased (-22 cmH2O, 95% CI: 7-38), while detrusor leak point pressure increased (+13 cmH2O, 95% CI: 2-25). Lower urinary tract symptoms showed inconsistent improvements. The certainty of evidence was low to very low for most outcomes due to study heterogeneity and methodological limitations.
conclusionElectrotherapy appears to improve bladder compliance, cystometric capacity, and detrusor pressure in children with neurogenic bladder due to spina bifida. However, due to the variability in study quality and intervention parameters, further high-quality research is needed to confirm its clinical efficacy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.