ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2025
The Effect of Iron Deficiency Anemia on the Morphology-Voltage-P Wave Duration (MVP) Risk Score.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- The Effect of Iron Deficiency Anemia on the Morphology-Voltage-P Wave Duration (MVP) Risk Score.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025Article
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5 authors.
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Abstract
backgroundIron deficiency anemia (IDA) is a common global health issue affecting over two billion people and is associated with cardiovascular complications. Electrocardiographic (ECG) abnormalities may reflect cardiac involvement in IDA. The Morphology-Voltage-P wave Duration (MVP) score, which assesses P-wave duration, voltage, and morphology, is linked to atrial fibrillation (AF) risk. This study aimed to investigate the relationship between IDA and MVP score to evaluate its potential in cardiac risk assessment.
methodsA prospective study was conducted between January 1 and June 30, 2024, at a tertiary hospital. It included 241 IDA patients and 204 healthy controls. All participants underwent ECG and echocardiography. MVP scores were calculated, and left atrial (LA) diameter and left ventricular ejection fraction (LVEF) were recorded.
resultsMVP scores were significantly higher in the IDA group compared to controls (p < 0.001). P-wave morphology and voltage were notably altered in IDA patients (p < 0.001). LA diameters were larger, and LVEF values were lower in the IDA group (p < 0.001). MVP scores positively correlated with LA size and negatively with LVEF. Additionally, IDA patients had higher heart rates and lower diastolic blood pressure (p < 0.001).
conclusionsIDA is associated with increased MVP scores, suggesting possible atrial remodeling and higher AF risk. The MVP score may serve as a non-invasive tool for cardiovascular risk stratification in IDA patients. Further research is needed to assess the impact of IDA treatment on ECG parameters and arrhythmia risk.
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