ArticleRenal failure2025
Fluid removal intensity in intermittent hemodialysis for acute kidney injury: net ultrafiltration rate characterization and outcomes.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In patients receiving continuous renal replacement therapy (CRRT) for acute kidney injury (AKI), excessive net ultrafiltration (NUF) rates >1.75 mL/kg/h have been associated with increased mortality, delayed AKI recovery and complications of hemodynamic instability. There is limited information on fluid removal practices and NUF rates in AKI patients treated with intermittent hemodialysis (IHD). We conducted a retrospective study of AKI patients who underwent IHD at our center between 2020 and 2023. The primary outcome was NUF rate, assessed as body weight-scaled, body surfaces area-scaled and unadjusted values. Secondary outcomes included mortality and measures of renal recovery at 90 days (estimated glomerular filtration rate [eGFR], major adverse kidney events [MAKE], IHD dependence and days to liberation from IHD). We studied 74 patients (median age 62 years [IQR 46-71], median baseline eGFR 81 mL/min/1.73 m Among AKI patients, median NUF rates during IHD was higher than reported for CRRT and influenced by comorbidity and pre-morbid eGFR. At 90 days, MAKE was common, two thirds of patients had
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