ArticleCureus2025
Comparative Evaluation of the Shear Bond Strength of Composite to Remineralized Dentin: An In Vitro Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Caries-affected dentin is a partially demineralized substrate that retains its collagen matrix and has the potential to be remineralized. Recent biomimetic materials have shown potential in enhancing remineralization and improving composite bonding. The study aimed to compare the shear bond strength of composite resin to demineralized dentin after remineralization with three agents: silver diamine fluoride (SDF), nanohydroxyapatite (nHAp), and self-assembling peptide P11-4 (SAP P11-4). Materials and methods An in vitro, non-randomized, experimental study was conducted using sixty premolars with a single root, collected post-extraction, and equally divided into four groups: control, SDF, nHAp, and SAP. Remineralizing agents were applied to exposed dentin surfaces, followed by the placement of composite resin. After surface treatment with remineralizing agents, the resin-based composite was applied, and a universal testing machine was utilized to determine the shear bond strength. The modes of failure were examined using a stereomicroscope. One-way ANOVA and Tukey's post hoc test were used (p < 0.001). Results The SAP P11-4 group showed the highest mean bond strength (28.13 N), followed by the SDF groups and nHAP groups, while the control group demonstrated the lowest values. All remineralized groups exhibited significantly higher bond strength compared to the control (p < 0.001). Intergroup comparisons revealed statistically significant differences among all test groups, with SAP P11-4 significantly outperforming SDF and nHAP. Failure mode analysis revealed that SAP P11-4 predominantly resulted in cohesive failure, whereas SDF and nHAP primarily exhibited adhesive failure. Conclusions Among the three remineralizing agents tested, SAP P11-4 demonstrated the highest shear bond strength to demineralized dentin. Its superior performance highlights its potential to enhance the longevity and durability of resin-based restorations in minimally invasive dentistry. The predominance of cohesive failure further supports its effectiveness in creating a strong, integrated bond between the composite resin and dentin substrate.
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