ArticleCureus2025
Beyond the Surface: Cutaneous Vasculitis as a Sign of a Fatal Underlying Condition.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cutaneous vasculitis can pose a significant diagnostic challenge due to its broad range of potential causes, including immune-mediated conditions, drug reactions, and infection-driven processes. Systemic infections can sometimes manifest initially with skin findings, including palpable purpura, petechiae, or necrotic lesions, which mimic primary vasculitic disorders. Distinguishing between infectious and non-infectious vasculitis is critical, as empirical immunosuppressive therapy in patients with an underlying infection can worsen outcomes and delay appropriate treatment. We report the case of an 81-year-old woman who presented with cutaneous vasculitis, which was ultimately found to be a manifestation of infective endocarditis affecting the aortic valve. This case highlights the need for clinicians to maintain a high index of suspicion for systemic infection, particularly infective endocarditis, in patients presenting with vasculitic skin lesions, as early recognition and appropriate antimicrobial therapy can significantly alter prognosis.
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