Evidence map›Paper›PMID 41084647›Full record

ArticleCureus2025

Merkel Cell Tumor: A Mystery Beneath the Surface.

Axel R Marquez-Nuñez, Nataly C Berrezueta Córdova, Nishdaly A Rodríguez Valencia, Elisa Vega-Memije, Leticia Boeta Ángeles

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Axel R Marquez-NuñezDepartment of Dermatology, National Autonomous University of Mexico, Mexico City, MEX.
Nataly C Berrezueta CórdovaDepartment of Dermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Nishdaly A Rodríguez ValenciaDepartment of Dermatology, Hospital Juárez del Centro, Mexico City, MEX.
Elisa Vega-MemijeDepartment of Dermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Leticia Boeta ÁngelesDepartment of Dermatology, Hospital Juárez del Centro, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is an aggressive skin condition that requires prompt diagnosis and management. It predominantly affects older adults and has a high propensity for recurrence and metastasis. The acronym AEIOU, which stands for asymptomatic, expanding rapidly, immunosuppression, older than 50 years, and UV radiation, is often used in the approach to diagnosis. We present a unique and intriguing case of a 70-year-old patient with a solitary and asymptomatic exophytic lesion on her right forearm that had been present for one year. She had not received any treatment or medical advice to date. Our case contributes to the literature on MCC, highlighting the variety of differential diagnoses that can occur in an atypical variety such as the one we are describing. We recall the relevance of the histopathological approach, emphasizing the crucial role of immunohistochemistry in the presumptive diagnosis of this entity.

Indexed as

cutaneous apudomamerkel cell carcinomaneuroendocrine carcinomaskin malignancytrabecular carcinoma of the skin

Identifiers

PMID41084647
PMCPMC12515491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.