Evidence map›Paper›PMID 41084502›Full record

ReviewJournal of multidisciplinary healthcare2025

Decoding the Solution for Man-at-the-End Attacks and Reverse Engineering on IoMT Devices: An Experimental Review of Techniques and Defences.

Agila Harshini T, Harini Sriraman

Abstract readReview
In one paragraph

Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Agila Harshini TDepartment of Computer Science and Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India.
Harini SriramanDepartment of Computer Science and Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India.ORCID 0000-0002-2192-8153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Internet of Medical Things (IoMT), which revolutionizes modern healthcare, is expanding to provide remote support and treatment options. The device is handled by the patient or the healthcare provider to monitor the data continuously. When the IoMT is not handled with care by the authorized person, the sensitive data can be compromised by Man-At-The-End attacks (MATE). The gain of physical access allows the attacker to insert malicious code and tamper with the normal functionality, leading to wrong diagnosis and treatment. The altered performance of the medical device causes direct harm to patients. The existing software solutions do not provide complete security when it comes to attacks that gain physical access to devices. Physically Unclonable Functions (PUF) and Field Programmable Gate Arrays (FPGA) based security offers protection by establishing robust authentication through customizable logic, real-time data processing, and obfuscation. Identifying MATE attacks that are resistant to PUF/FPGA protection is crucial to offering a robust and resilient solution. The classification of critical MATE attacks specific to IoMT devices, Experimental validation using hardware platforms like Arduino Uno, Raspberry Pi, and ESP32 for reverse engineering is performed. Existing security measures available to protect the healthcare device, and how FPGA and PUF can provide better security against MATE attacks are explained. This paper uniquely reviews a thorough analysis of the vulnerability of PUF-enabled IoMT devices in the face of MATE attacks is presented. Possible futuristic solutions such as tamper-proof hardware, evolvable PUF, and AI-assisted anomaly detection for the identified problems, with experimental findings and security assessments, offer practical insights.

Indexed as

cyber threatFPGAIoMT vulnerabilitiesPUF security

Identifiers

PMID41084502
PMCPMC12515419

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.