Evidence map›Paper›PMID 41084264›Full record

ReviewCurrent pharmaceutical design2026

Effect of Lavender Essential Oil-based Aromatherapy on Anxiety: An Overview of Results of Recent Randomized Controlled Trials.

Bhagavathi Sundaram Sivamaruthi, Chaiyavat Chaiyasut, Natarajan Suganthy, Athit Bunyakitcharoen, Wipada Kunaviktikul, Areewan Klunklin, Pranom Fukngoen, Periyanaina Kesika

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bhagavathi Sundaram SivamaruthiOffice of Research Administration, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chaiyavat ChaiyasutInnovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Natarajan SuganthyBionanomaterials Research Lab, Department of Nanoscience and Technology, Alagappa University, Karaikudi, 630003, India.
Athit BunyakitcharoenInnovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Wipada KunaviktikulPanyapiwat Institute of Management, Nonthaburi, 11120, Thailand.
Areewan KlunklinSchool of Nursing, Panyapiwat Institute of Management, Nonthaburi, 11120, Thailand.
Pranom FukngoenOffice of Research Administration, Chiang Mai University, Chiang Mai, 50200, Thailand.
Periyanaina KesikaOffice of Research Administration, Chiang Mai University, Chiang Mai, 50200, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs) are plant-derived bioactive compounds, primarily made up of terpenoids, which possess various biological and pharmacological effects. Lavender essential oil (LEO) is one of the most extensively studied options. LEO contains terpenes, ketones, alcohols, polyphenols, and flavonoids. Aromatherapy, a practice dating back to ancient civilizations such as the Egyptians, Romans, and Chinese, involved the use of incense, baths, and embalming rituals. Anxiety disorders have gained significant attention in understanding both physical and mental health. Many people are turning to complementary and alternative therapies for the management of anxiety due to the side effects of pharmacological treatments. Several preclinical studies suggest that LEO may alleviate anxiety-like behaviors in experimental models. This review examines the chemical composition, pharmacological properties, and mechanisms of LEO that contribute to its role in managing anxiety in humans. The literature indicates that LEO-based aromatherapy may effectively reduce anxiety in various groups, such as nursing students, patients undergoing surgery, and those involved in clinical procedures. While the exact mechanisms behind LEO's anxiolytic effects remaining unclear, active compounds in EOs may influence the production and release of neurotransmitters through pathways involving γ-aminobutyric acid, dopamine, and serotonin. More extensive preclinical and clinical studies with diverse subject groups are needed to better understand the molecular mechanisms of LEO's anxiolytic properties, which could ultimately help in developing optimized treatments for managing anxiety disorders.

Indexed as

Anti-Anxiety AgentsAnxietyAnxiety DisordersAromatherapyLavandulaOils, VolatilePlant OilsAnimalsHumansRandomized Controlled Trials as TopicAnti-Anxiety Agentslavender oilOils, VolatilePlant OilsAnxietyAromatherapyEssential oilLavenderSerotoninγ-aminobutyric acid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.