ArticleJournal of microbiology and biotechnology2025
Nanobody-Functionalized Magnetic Beads for Enrichment of Foodborne Botulinum Toxin Type A Light Chain.
Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
In this study, for the first time, nanobody conjugated beads were developed to enrich botulinum serotype A. We evaluated two types of nanobody A8-functionalized magnetic beads, both of which effectively captured and enriched BoNT/A from dilute solutions and complex protein mixtures, achieving a concentration increase of approximately 12- to 30-fold. The A8@N-beads showed higher binding capacity than the A8@S-beads, suggesting that our self-synthesized NH
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