ArticleJournal of nanobiotechnology2025
Decellularized extracellular matrix bio-patch with strong and biodegradable wet adhesive interface for sutureless soft tissue defect repair.
Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Benchmarking of Decellularization Protocols for Small Intestinal Submucosa: Defining the Gold Standard for Functional Tissue Engineering.Materials (Basel, Switzerland) · 2026Article
- A robust asymmetric bioadhesive patch for sutureless intestinal repair to prevent anastomotic leakage and postoperative adhesion.Theranostics · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Decellularized extracellular matrix-based bio-patches offer superior biocompatibility and bioactivity, making them an ideal implantation material for soft tissue defect repair. However, the fixation of these patches typically relies on sutures or staplers, causing secondary tissue damage, stress concentration, and excessive inflammatory cell infiltration. Here, we develop a novel self-adhesive small intestinal submucosa patch (A-SIS) fabricated by in situ polymerizing a biodegradable hydrogel adhesive layer on the surface of the SIS patch. The A-SIS demonstrated increased tensile strength, biodegradability, and strong wet adhesion to various soft tissues (including skin, heart, stomach, and intestine), with shear strength reaching 100 kPa and interfacial toughness of 700 J/m
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Registered trials
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