Evidence map›Paper›PMID 41084037›Full record

ReviewEye and vision (London, England)2025

International consensuses and guidelines on diagnosing and managing fungal endophthalmitis by the Asia-Pacific Vitreo-retina Society (APVRS), the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII).

Taraprasad Das, Nishant V Radke, Ahmed B Sallam, Andrew Chang, Andrzej Grzybowski, Bahram Bodaghi, Chi-Chun Lai, Harry Flynn, Han Joo Cho, Hiroto Ishikawa and 14 more

Abstract readReview
In one paragraph

Review in Eye and vision (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Taraprasad DasDepartment of Vitreoretinal Services, Shantilal Shanghvi Eye Institute, Mumbai, India. tpdbei@gmail.com.
Nishant V RadkeThe Primasia International Eye Research Institute (PIERI), The Chinese University of Hong Kong (Shenzhen), Longxiang Boulevard, Longgang District, Shenzhen, 2001, China.
Ahmed B SallamDepartment of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Andrew ChangSydney Retina Clinic, Sydney Eye Hospital, University of Sydney, Sydney, NSW, Australia.
Andrzej GrzybowskiInstitute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland.
Bahram BodaghiDepartment of Ophthalmology, Pitié-Salpêtrière University Hospital, Sorbonne University, Paris, France.
Chi-Chun LaiDepartment of Ophthalmology, Linkou Main Branch, Chang Gung Memorial Hospital, Taoyuan, Taiwan, China.
Harry FlynnDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Han Joo ChoDepartment of Ophthalmology, Kim's Eye Hospital, Youngdeungpo-Gu, Seoul, South Korea.
Hiroto IshikawaJ-CREST (Japan Clinical REtina STudy Group), Kagoshima, Japan.
Hua YanDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China.
Joveeta JosephJhaveri Microbiology Centre, Brien Holden Eye Research Center, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Kuan-Jen ChenDepartment of Ophthalmology, Linkou Main Branch, Chang Gung Memorial Hospital, Taoyuan, Taiwan, China.
Landon J RohowetzDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Li Jia ChenDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Liuxueying ZhongState Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology Visual Science, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.
Matthew P SimunovicSave Sight Institute, Sydney Eye Hospital Campus, Sydney, NSW, Australia.
Paisan RuamviboonsukRetina Division, Department of Ophthalmology, Faculty of Medicine, Rajvithi Hospital, Rangsit University, Bangkok, Thailand.
Prashanth IyerDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Robert F LamDepartment of Ophthalmology, Caritas Medical Center, Hong Kong, China.
Rupesh AgrawalNational Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.
Vivek P DaveAnant Bajaj Retina Institute, Srimati Kanuri Santhamma Center for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Xiangyu ShiBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Science Key Lab, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.
Dennis S C LamThe Primasia International Eye Research Institute (PIERI), The Chinese University of Hong Kong (Shenzhen), Longxiang Boulevard, Longgang District, Shenzhen, 2001, China. dennislam@pieri.cuhksz.org.ORCID http://orcid.org/0000-0001-5276-3702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal endophthalmitis represents one of the most challenging intraocular infections to diagnose and manage in ophthalmology. Despite advances in diagnostic techniques and treatment options, numerous controversies persist regarding optimal approaches to this sight-threatening condition. Due to the low incidence and significant variation in the severity and time of presentations, no large-scale randomized controlled trials have been done. Therefore, identifying controversies and deliberating the best approach to diagnosing and treating fungal endophthalmitis by international experts would help establish consensus statements that can guide clinical practice. The Asia-Pacific Academy of Professors in Ophthalmology (AAPPO), Asia-Pacific Vitreo-Retina Society (APVRS), and Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) saw this critical gap and formed an international panel of experts comprising 24 experts to establish 20 consensus statements. While there is consensus on the need for early diagnosis and prompt administration of antifungal therapy, there are conflicting views on the optimal diagnostic approach to be taken, the role and timing of performing vitrectomy, and the use of systemic antifungal agents. A particularly contested topic is the role of corticosteroids. In establishing the 20 consensus statements, these thus serve as guidelines for diagnosing and managing fungal endophthalmitis.

Indexed as

AAPPOAPSOIIAPVRSConsensusControversyDiagnosisFungal endophthalmitisManagement

Identifiers

PMID41084037
PMCPMC12516872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.