Evidence map›Paper›PMID 41084028›Full record

ArticleBMC complementary medicine and therapies2025

Chemical profiling and multidirectional biological effects of the aerial parts of two wild Commicarpus species; C. grandiflorus and C. plumbagineus.

Reham Hassan Mekky, Ahmed H El-Desoky, Riham A El-Shiekh, Meselhy R Meselhy, Essam Abdel-Sattar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reham Hassan MekkyDepartment of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Cairo-Suez Road, Badr City, Cairo, 11829, Egypt.
Ahmed H El-DesokyPharmacognosy Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Buhouth Street, Dokki, Giza, 12622, Egypt.
Riham A El-ShiekhDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, El Kasr El-Aini Street, Cairo, 11562, Egypt.
Meselhy R MeselhyDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, El Kasr El-Aini Street, Cairo, 11562, Egypt.
Essam Abdel-SattarDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, El Kasr El-Aini Street, Cairo, 11562, Egypt. essam.abdelsattar@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-0617-1420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommicarpus grandiflorus (A.Rich.) Standl. (CG), and Commicarpus plumbagineus (Cav.) Standl. (CP) (Nyctaginaceae family) have long been utilized in traditional medicine for the treatment of various ailments, including urinary tract infections, dysmenorrhea, and blood coagulation disorders.

methodsThe chemical composition of the aerial parts of both plants, total phenolic and flavonoid contents were determined. The antioxidant effects of total methanolic extracts and fractions obtained thereof; methylene chloride (MC) and remaining water (RW) fractions, and their inhibitory potentialson COX-1, COX-2, LOX, ACh, BuCh, and α-glucosidase, were assessed.

resultsThe RW fractions of CP and CG exhibited the highest phenolic (57.19 ± 2.43-60.19 ± 1.5 µg GAE/mg) and flavonoid contents (44.32 ± 1.8-53.99 ± 1.8 µg QE/mg), respectively. Also, both fractions demonstrated remarkable antioxidant effects; ABTS

conclusionsBoth samples showed enzyme inhibitory potential against key enzymes linked to chronic diseases. The findings highlight the significant potential of both CG and CP, warranting further research for drug development and biomedicines.

Indexed as

AntioxidantsPlant Components, AerialPlant ExtractsFlavonoidsPhenolsAntioxidantsFlavonoidsPhenolsPlant ExtractsBioactive agentCommicarpus grandiflorusCommicarpus plumbagineusNatural enzyme inhibitorsPhenolic composition

Identifiers

PMID41084028
PMCPMC12516866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.