Evidence map›Paper›PMID 41083980›Full record

ArticleMicrobial cell factories2025

Solution towards low yield biosurfactant production from bacteria, a novel approach using microalgae-bacteria consortium.

Yan Jer Ng, Kuan Shiong Khoo, Kit Wayne Chew, Doris Ying Ying Tang, Sarah Alharthi, Andres Philip Mayol, Pau Loke Show

Abstract read
In one paragraph

Article in Microbial cell factories, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan Jer NgDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Kuan Shiong KhooDepartment of Chemical Engineering and Materials Science, Yuan Ze University, Taoyuan, Taiwan. kuanshiong.khoo@saturn.yzu.edu.tw.
Kit Wayne ChewDepartment of Chemical and Petroleum Engineering, United Arab Emirates University (UAEU), PO Box, 15551, Al Ain, United Arab Emirates.
Doris Ying Ying TangDepartment of Chemical Engineering, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates.
Sarah AlharthiDepartment of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.ORCID http://orcid.org/0000-0001-9373-1811
Andres Philip MayolDepartment of Manufacturing Engineering and Management, De La Salle University, 1004, Manila, Philippines.
Pau Loke ShowDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia. PauLoke.Show@nottingham.edu.my.

Funding

Khalifa University of Science, Technology and Research 8474000580
6 · The paper itself

Abstract

backgroundSurfactants are an important chemical in the industry due to their unique properties to reduce surface tension between fluids. To date, raw materials involved for the synthesis of surfactants are mostly derived from petroleum-based compounds. Although the current petroleum reserve can sustain annual consumption, petroleum is a non-renewable resource thus a sustainable alternative is needed. Current research has been focusing on exploring alternative biological feedstock for biosurfactants derived from microbes. However, these biosurfactants are usually from bacteria having either low yield or from pathogenic bacteria. This research aims to assess the potential of Bacillus subtilis-Desmodesmus perforatus consortium to produce biosurfactants at a higher efficiency compared to pure bacteria.

resultsResults showed that the co-cultivation of bacteria with microalgae increases the yield of biosurfactants from 0.0207 ± 0.0124 g/100mL to 0.4584 ± 0.0205 g/100mL. Subsequent parameters including microalgae species, volume of microalgae or bacteria inoculated, volume and concentration of culture medium were optimized to increase the final yield of biosurfactant to achieve a yield of 0.7109 ± 0.0215 g/100 mL, far higher than the yield of biosurfactants produced by pure bacteria culture, proving that microalgae-bacteria consortium provides a solution to increase the yield of biosurfactants from non-pathogenic bacteria.

conclusionThis study has proven the potential of using a microalgae-bacteria consortium to produce glycolipids at an industrial feasible rate, which can help in reducing the reliance of the commercial petroleum-based surfactants.

Indexed as

Bacillus subtilisBacteriaMicroalgaeMicrobial ConsortiaSurface-Active AgentsSurface-Active AgentsBacillus subtilisBiosurfactant productionCultivationDesmodesmus perforatusGlycolipidRhamnolipid

Identifiers

PMID41083980
PMCPMC12519745

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.