Evidence map›Paper›PMID 41083935›Full record

ArticleBMC infectious diseases2025

Desensitization reduces some COVID-19-associated symptoms in minors with allergic rhinitis.

Shipeng Zhang, Mengni Zhang, Qiqi Liu, Xiaocui Wang, Junyu Xiang, Qinxiu Zhang, Min Hu

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shipeng Zhang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Mengni Zhang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Qiqi LiuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Xiaocui WangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Junyu XiangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Qinxiu ZhangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China.
Min HuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, P. R. China. China.5340@cdutcm.edu.cn.

Funding

Health Commission of Chengdu and Chengdu University of Traditional Chinese Medicine WXLH202403138
6 · The paper itself

Abstract

objectiveThis cross-sectional study aimed to investigate the symptoms following COVID-19 infection among pediatric and adult allergic rhinitis (AR) patients undergoing different treatment regimens—specifically sublingual immunotherapy (SLIT) versus conventional pharmacological treatment.

methodsA total of 398 patients diagnosed with AR were included from the clinical database and categorized according to treatment type: an SLIT group (AR-S), further stratified into AR-S1 (< 18 years) and AR-S2 (≥ 18 years), and a control group (AR-C). Between December 2022 and February 2023, data on respiratory and general symptoms following SARS-CoV-2 infection were collected and compared across groups.

resultsThe AR-S1 group may be associated with a reduced risk of symptoms after infection including dry throat (OR = 0.373, 95%Cl:0.184–0.755), headache (OR = 0.385, 95%Cl:0.196–0.758), fatigue (OR = 0.376, 95%Cl:0.188–0.751), chest tightness (OR = 0.160, 95%Cl:0.049–0.522), and some symptoms after improvement of infection (cough, fatigue).

conclusionMinor AR patients with SLIT can reduce some of the symptoms in COVID-19-infected patients.

Indexed as

COVID-19Rhinitis, AllergicSublingual ImmunotherapyAdolescentAdultChildCross-Sectional StudiesFemaleHumansMaleSARS-CoV-2Allergic rhinitisCOVID-19MinorsOdds ratioSublingual immunotherapy

Identifiers

PMID41083935
PMCPMC12516878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.