Observational studyBMC gastroenterology2025
Unmasking the role of constipation in treatment-refractory enterobiasis in Bangladeshi children.
Observational study in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelminthiasis remains a prevalent health issue among the pediatric population in both developed and developing countries. Recurrent enterobius vermicularis infection is a particularly distressing and sometimes embarrassing condition for children. While sporadic cases are common, repeated infections despite proper hygiene and regular deworming are uncommon and warrant further investigation.
methodsThis prospective observational study was conducted in Sylhet, Bangladesh between January 2022 and December 2024. All consecutive children presenting with treatment-refractory enterobiasis were enrolled. Comprehensive clinical evaluations and relevant investigations were performed to identify potential underlying or contributory factors. Treatment strategies were tailored accordingly, and clinical response was assessed based on symptom resolution.
resultsA total of 114 children were included, with a mean age of 88.25 ± 37.5 months and a male-to-female ratio of 1.65:1. All children presented with perianal itching and visible passage of worms (100%). Additional symptoms included abdominal pain (64%), anorexia (51%), vomiting (24%), nausea (16%), frequent small-volume defecation (9%), increased frequency of micturition (9%), nocturnal enuresis(7%), and encopresis (7%). Notably, constipation was present in 96% of cases-41% with occult and 55% with overt constipation (p < 0.0001), all of which had either been previously unrecognized or inadequately managed. Following the administration of appropriate laxative therapy along with antihelminthic therapy, significant symptomatic improvement was observed (p < 0.0001) with minimal failure rate (3%).
conclusionConstipation frequently coexists in patients with treatment-refractory enterobius vermicularis infections and proper management of constipation is essential for successful therapeutic outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.