Evidence map›Paper›PMID 41083881›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Oxygen dynamics in paraspinal muscles during isometric loading measured using near-infrared spectroscopy in adolescents with idiopathic scoliosis: SOSORT 2025 award winner.

Winnie Wai-Ying Chan, Eliza Rui Sun, Siu-Ngor Fu, Yong-Ping Zheng, Eric C Parent, Jason Pui-Yin Cheung, Arnold Yu-Lok Wong

Abstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Winnie Wai-Ying ChanDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, SAR, Hong Kong, China. ptwinnie05.chan@connect.polyu.hk.
Eliza Rui SunDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, SAR, Hong Kong, China.
Siu-Ngor FuDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, SAR, Hong Kong, China.
Yong-Ping ZhengDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, SAR, Hong Kong, China.
Eric C ParentDepartment of Physical Therapy, University of Alberta, Edmonton, AB, China.
Jason Pui-Yin CheungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, SAR, Hong Kong, China.
Arnold Yu-Lok WongDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, SAR, Hong Kong, China. arnold.wong@polyu.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeParaspinal muscle imbalances in teenagers with adolescent idiopathic scoliosis (AIS) are well-documented, but their metabolic characteristics remain unclear. This study assessed oxygen recovery asymmetry (TrAsy) in paraspinal muscles during isometric trunk extension in teenagers with and without AIS and explored its correlation with spinal curvature.

methodsFifty-one AIS participants with primary right thoracic curves (40 females; 13.5 ± 1.7 years; thoracic Cobb angles: 22.9°±6.8°; 28 mild [Cobb angles 10°-24°], 23 moderate-to-severe [≥ 25°]) and 51 non-AIS controls (33 females; 13.2 ± 1.7 years) performed prone isometric trunk extensions. Bilateral paraspinal oxygen recovery times (Tr) at T9 and L3 were measured using near-infrared spectroscopy. TrAsy (between-side Tr difference) was analyzed using mixed-design ANOVA with group (AIS vs. controls) and side (convex vs. concave) factors; Welch's ANOVAs assessed TrAsy differences by curve severity and location. The association between thoracic Cobb angles and TrAsy was evaluated using multiple linear regression, adjusting for covariates.

resultsAIS cases (Cobb angles: 22.9°±6.8°) showed significantly longer Tr on the concave side at T9 (74.6s ± 10.1s vs. 50.1s ± 16.8s; p < 0.001), with no significant between-side difference at L3 in both groups analyzed collectively (p = 0.31). Tr was longer at T9 than L3 (p < 0.001) Single curves exhibited greater TrAsy than double curves at T9 (mean difference: 25.0s ± 8.60s; p = 0.004), with moderate-severe AIS showing larger concave-side Tr. The regression model showed that greater TrAsy was associated with larger thoracic Cobb angles (R

conclusionTeenagers with AIS showed greater TrAsy at T9, predominantly on the concave side, which correlated with curve severity. Further research should investigate causal relation between metabolic response and curvature progression.

Indexed as

Isometric ContractionOxygenParaspinal MusclesScoliosisAdolescentChildFemaleHumansMaleSpectroscopy, Near-InfraredOxygenMuscle oxygenationNear-infrared light spectroscopyOxygen dynamics asymmetryParaspinal muscleScoliosis

Identifiers

PMID41083881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.