Evidence map›Paper›PMID 41083664›Full record

ArticleJournal of assisted reproduction and genetics2025

Comparison of clinical outcome after intrauterine insemination with donor semen in single women, lesbian couples and heterosexual couples.

M Godinho, M Chaillot, S Bouée, A Reignier, T Fréour

Abstract readMulticenter Study
In one paragraph

Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M GodinhoService de médecine et biologie de la reproduction, CHU de Nantes, Nantes Université, Nantes, 44093, France.
M ChaillotService de médecine et biologie de la reproduction, CHU de Nantes, Nantes Université, Nantes, 44093, France.
S BouéeCentre d'AMP, CHRU de Brest, 2 Avenue Foch, Brest, 29200, France.
A ReignierService de médecine et biologie de la reproduction, CHU de Nantes, Nantes Université, Nantes, 44093, France.
T FréourService de médecine et biologie de la reproduction, CHU de Nantes, Nantes Université, Nantes, 44093, France. thomas.freour@chu-nantes.fr.ORCID http://orcid.org/0000-0002-7243-7709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to compare clinical pregnancy rate after IUI-D in heterosexual couples (HC), lesbian couples (LC), and single women (SW).

methodsThis retrospective multicentric study was conducted in two university-based ART centers in France in all consecutive IUI-D cycles performed after stimulation with gonadotropins in 2021-2023. The primary outcome was clinical pregnancy rate (CPR). Cumulative clinical pregnancy rate was also calculated. Comparisons were made between groups taking HC as the control group and adjusting for age.

resultsA total of 962 patients undergoing 2737 IUI-D cycles were included in the analysis, 234 HC women (24.3%), 478 LC women (49.7%), and 250 (30%) single women (SW). SW were significantly older than HC and LC. Clinical pregnancy rate (CPR) per cycle was significantly lower in LC and SW than in HC in univariate analysis. Age was negatively associated with clinical pregnancy. After adjusting for age, no statistically significant relationship was found between category and clinical pregnancy (p = 0.07). Cumulative clinical pregnancy rates (CCPR) and the average number of cycles required to achieve pregnancy were not significantly different between HC, LC and SW.

conclusionsThis first study conducted in France after change in law allowing ART access for LC and SW confirms that CPR after IUI-D is not significantly associated with relationship status after adjusting for age.

Indexed as

HeterosexualityInsemination, ArtificialInsemination, Artificial, HeterologousSemenAdultFemaleFertilization in VitroFranceHumansMalePregnancyPregnancy RateRetrospective StudiesSexual and Gender MinoritiesSingle PersonDonor inseminationIntrauterine inseminationLesbian couplePregnancySingle women

Identifiers

PMID41083664
PMCPMC12705500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.