ArticleScientific reports2025
Impact of comorbid depression and anxiety on temporomandibular disorders related pain, sleep, function, behaviors, and quality of life.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative effectiveness of nonpharmacological therapies for adult myogenic temporomandibular disorders: a network meta-analysis of randomized trials.BMC oral health · 2026Pooled it
- Oral Behaviors, Anxiety, and Depression in Temporomandibular Disorders: A Conceptual Narrative Review Within the DC/TMD Axis II Framework.Medicina (Kaunas, Lithuania) · 2026Review
- Latent profiles of oral health-related quality of life in temporomandibular disorders: implications for nurse-led stratified care.BMC nursing · 2026Article
- Baseline Oral Behaviours in Relation to Follow-Up Temporomandibular Joint Disease Severity After Intra-Articular I-PRF: A Baseline-Adjusted Exploratory Cohort Study.Journal of clinical medicine · 2026Article
- Cognitive and Orofacial Intersections: prevalence of temporomandibular disorders and bruxism in individuals with symptoms of attention deficit hyperactivity disorder.Journal of applied oral science : revista FOB · 2026Article
- Threshold Effect of Anxiety in the Comorbidity of Depression and Chronic Pain: A Cross-Sectional Study Based on Pain Sensitivity.Neuropsychiatric disease and treatment · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
This study examined the prevalence of comorbid depression and anxiety in Chinese patients with temporomandibular disorders (TMDs), and their associations with pain intensity, sleep propensity, oral behaviors, jaw function, and oral health-related quality of life (OHRQoL). It also evaluated the likelihood of different TMD subtypes among individuals with no depression or anxiety (NC), depression alone (DA), anxiety alone (AA), and comorbid conditions (CC). Participants recruited from a dental hospital completed a survey comprising sociodemographics, the Diagnostic Criteria for TMDs (DC/TMD) Symptoms Questionnaire, Patient Health Questionnaire-9, Generalized Anxiety Disorder Scale-7, Numerical Pain Rating Scale, Epworth Sleepiness Scale, Oral Behaviors Checklist, Jaw Functional Limitation Scale-8, and the Oral Health Impact Profile for TMDs. Clinical examinations followed the DC/TMD protocol, classifying individuals into intra-articular (IT), pain-related (PT), or combined (CT) TMDs. Statistical analyses included chi-square tests, non-parametric methods, and multinomial logistic regression (α = 0.05). Among 798 participants (mean age 29.8 years [SD 10.7]; 79.6% women), 48.0%, 10.8%, 7.9%, and 33.3% had NC, DA, AA, and CC, respectively. Significant differences were observed in pain intensity (CC/AA/DA > NC), sleep propensity (CC/DA > AA/NC), jaw overuse behavior (CC > AA/NC; DA > NC), jaw functional limitation (CC > DA > NC; AA > NC), and OHRQoL (CC > AA > DA > NC). Moderate correlations were observed between jaw functional limitation and OHRQoL across groups, with additional links to pain intensity in DA and AA (r
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