Evidence map›Paper›PMID 41083567›Full record

ArticleScientific reports2025

Secure and interpretable lung cancer prediction model using mapreduce private blockchain federated learning and XAI.

Khan Muhammad Adnan, Taher M Ghazal, Muhammad Saleem, Muhammad Sajid Farooq, Chan Yeob Yeun, Munir Ahmad, Sang-Woong Lee

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Khan Muhammad AdnanPattern Recognition and Machine Learning Lab, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam-si, 13557, Republic of Korea.
Taher M GhazalDepartment of Networks and Cybersecurity, Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, Jordan.
Muhammad SaleemChitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, 140401, Punjab, India.
Muhammad Sajid FarooqDepartment of Cyber Security, NASTP Institute of Information Technology, Lahore, 58810, Pakistan.
Chan Yeob YeunCentre for Secure Cyber-Physical Systems (C2PS), Computer Science Department, Khalifa University, Abu Dhabi, United Arab Emirates. chan.yeun@ku.ac.ae.
Munir AhmadUniversity College, Korea University, Seoul, 02841, Republic of Korea.
Sang-Woong LeePattern Recognition and Machine Learning Lab, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam-si, 13557, Republic of Korea. slee@gachon.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer continues to be one of the most widespread and deadly cancer diagnoses that affects humans worldwide. Early detection of lung cancer leads to decreased mortality rates; however, several challenges hinder the development and deployment of effective predictive models. These challenges consist of mainly the problem of high computational power to evaluate large-scale medical data, privacy and security of medical data, limited data sharing between medical organizations and interpretability to handle the black box problem that AI-based models face. Such limitations have posed severe difficulties to the utilization of conventional approaches in the prediction of lung cancer, thus limiting them most importantly for general use, especially in clinical practice settings in real time. To address these challenges, this research introduced a novel lung cancer prediction model that utilizes an integrated framework combining MapReduce, Private Blockchain, Federated Learning (FL), and Explainable Artificial Intelligence (XAI). It improves lung cancer detection using MapReduce to handle large lung cancer datasets, supporting rapid and scalable learning. Private Blockchain is used for the secure, tamper-proof, and immutable processing of patient information, whereas FL allows healthcare sectors to train models together, without compromising patients' privacy. Moreover, it also employed XAI to improve the model's interpretability so clinicians can understand and rely on AI predictions. Together, these methods improve AI's efficiency and trustworthiness in medical applications. This proposed model provides better and more secure lung cancer predictions, ensuring interpretability and collaboration. With an exceptional accuracy of 98.21% and a miss rate of just 1.79%, it outperforms previously published approaches, establishing a new benchmark for privacy-preserving, explainable, and scalable AI models in healthcare.

Indexed as

Artificial IntelligenceBlockchainLung NeoplasmsAlgorithmsComputer SecurityEarly Detection of CancerFederated LearningHumansFederated learningLung cancer predictionMapReducePrivate blockchainXAI

Identifiers

PMID41083567
PMCPMC12518573

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.