Trial reportScientific reports2025
Predictive factors of successful tympanoplasty and quality of life outcomes in adults with dry perforation: a randomised clinical trial.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Understanding clinical outcomes following tympanoplasty is essential for effectively counseling patients and providing a comprehensive perspective on its benefits and limitations. To evaluate the effects of tympanoplasty on ear-related clinical symptoms, hearing function, health-related quality of life (HRQol), and symptoms of depression and anxiety. A randomized, non-blinded clinical trial was conducted. Patients scheduled for tympanoplasty were compared with a control group of individuals on the surgical waiting list. A single academic tertiary care center. The study included 111 participants (41 males [36.94%], 70 females [63.06%]; mean age = 34.41 ± 12.78 years) with dry tympanic membrane perforations. Among them, 63 underwent tympanoplasty, with success and failure rates of 33:18 (64.71%: 35.29%) at 3 months, and 22:16 (57.89%: 42.11%) at 6 months. The remaining 48 served as controls, with 43 (89.58%) followed up at 3 months. Tympanoplasty was evaluated at three time points-preoperatively (T0), and postoperatively at 3 months (T3) and 6 months (T6). Primary outcomes included scores from the Arabic version of the Ear Outcome Survey-16 (EOS-16) and the Arabic Version of the Hospital Anxiety and Depression Scale (HADS), assessed at T0, T3, and T6. For successful tympanoplasty: the Overall
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