ArticleBMJ open2025
Impact of social determinants of health on sepsis outcomes: a retrospective study of a single centre in the USA.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
objectivesSocial determinants of health (SDOH) factors are known to influence patient outcomes, but their effect on sepsis remains insufficiently studied. This research aims to investigate the relationship between SDOH factors and sepsis outcomes, highlighting opportunities to reduce health disparities and enhance patient care.
designRetrospective study.
settingLevel I trauma centre in Baton Rouge, Louisiana, USA.
participantsPatients with sepsis aged 18-89 years. Patients discharged or transferred to hospice were excluded to prevent bias and misinterpretation of the findings. MAIN EXPOSURE MEASURES: Social Vulnerability Index (SVI), the Gini Index and the average distance to the nearest urgent care, emergency department and clinic.
main outcome measuresIn-hospital mortality, 30-day readmission and hospital length of stay (LOS).
methodsχ
resultsDistance from urgent care is significantly associated with mortality (4.14 vs 3.24 miles, p<0.001). Higher SVI is significantly associated with longer LOS (HR=0.846, 95% CI 0.743 to 0.963, p=0.011). Distance from urgent care is also significantly associated with a longer LOS (HR=0.991, 95% CI 0.986 to 0.996, p=0.001).
conclusionMortality and LOS are closely linked to proximity to urgent care, while high SVI is notably associated with longer LOS. These findings highlight the significant impact of SDOH factors on sepsis outcomes and underscore the need for targeted interventions to address disparities in healthcare access and contextual health practices.
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