Evidence map›Paper›PMID 41083085›Full record

ArticleAnnals of epidemiology2025

Cardiovascular disease mortality trends in young adults aged 18-34 years, United States, 2000-2023.

Adam S Vaughan, Nicholas Sutton, Rebecca C Woodruff, LaTonia C Richardson, Janet S Wright, Fátima Coronado

Abstract read
In one paragraph

Article in Annals of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam S VaughanDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States. Electronic address: xha4@cdc.gov.
Nicholas SuttonDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States; Oak Ridge Institute for Science and Education, Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, United States.
Rebecca C WoodruffDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States.
LaTonia C RichardsonDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States.
Janet S WrightDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States.
Fátima CoronadoDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Chamblee, GA, United States.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

purposeThis study examines national trends in mortality from cardiovascular disease (CVD) and select subtypes among U.S. young adults aged 18-34 years from 2000 to 2023.

methodsNational mortality data from the National Vital Statistics System were used to identify CVD, heart disease, stroke, and hypertension-related CVD deaths among U.S. residents aged 18-34 from 2000 to 2023. Crude and age-standardized death rates were calculated overall and by age group, sex, and race and ethnicity. Temporal trends were calculated as percent change using a log-linear model.

resultsFrom 2000-2023, age-standardized CVD and heart disease death rates among young adults did not statistically change (percent change: -2.2 % [95 % CI: -7.8, 3.7] and -2.4 % [95 % CI: -8.3 %, 3.8 %], respectively). Stroke death rates decreased (percent change: -15.7 % [-21.0 %, -10.0 %])). However, hypertension-related CVD death rates increased by 78.5 % [95 % CI: 63.6 %, 94.7 %]). Patterns across demographic groups were broadly similar.

conclusionDespite stability or modest declines in CVD death rates among young adults, hypertension-related CVD death rates increased sharply during 2000-2023. These findings merit public health action and underscore the need for better identification and management of hypertension and other CVD risk factors among young adults.

Indexed as

Cardiovascular DiseasesAdolescentAdultAge DistributionCause of DeathFemaleHumansHypertensionMaleMortalitySex DistributionStrokeUnited StatesYoung AdultCardiovascular diseaseMortalityPublic health surveillanceTrendsYoung adults

Identifiers

PMID41083085
PMCPMC13072439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.