Evidence map›Paper›PMID 41082920›Full record

Trial reportEndoscopy2026

A prospective study evaluating an artificial intelligence-based system for withdrawal time measurement.

Ioannis Kafetzis, Philipp Sodmann, Bianca-Elena Herghelegiu, Michela Pauletti, Markus Brand, Katrin Schöttker, Wolfram G Zoller, Jörg Albert, Alexander Meining, Alexander Hann

Abstract readClinical Trial
In one paragraph

Trial report in Endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ioannis Kafetzis *Interventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Philipp Sodmann *Interventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Bianca-Elena HerghelegiuInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Michela PaulettiInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Markus BrandInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.ORCID 0000-0002-3495-5206
Katrin SchöttkerInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Wolfram G ZollerDepartment of Internal Medicine and Gastroenterology, Katharinenhospital, Stuttgart, Germany.
Jörg AlbertDepartment of Internal Medicine and Gastroenterology, Katharinenhospital, Stuttgart, Germany.
Alexander MeiningInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Alexander HannInterventional and Experimental Endoscopy (InExEn), Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.ORCID 0000-0001-8035-3559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Withdrawal time has emerged as a critical quality measure in colonoscopy for colorectal cancer screening. Owing to the high variability in calculating withdrawal time, recent research has explored the use of artificial intelligence (AI) to standardize this process, but prospective validation is lacking. Methods: This prospective, superiority trial compared the accuracy of AI-assisted withdrawal time calculation with that of physicians during routine colonoscopy from December 2023 to March 2024. The gold standard was obtained via manual, frame-by-frame annotation of the examination video recordings. The AI also automatically generated an image report, which was qualitatively assessed by four endoscopists. Results: 126 patients were analyzed. The proposed AI system demonstrated a significantly lower mean absolute error (MAE) in estimating withdrawal time compared with physicians (2.2 vs. 4.2 minutes; P < 0.001). This was attributed to examinations containing endoscopic interventions, where the AI had significantly lower MAE compared with physicians (2.1 vs. 5.2; P < 0.001). The MAE was comparable in the absence of interventions (2.3 vs. 2.3; P = 0.52). High-quality image reports were generated by the AI system; 97% were assessed as showing satisfactory timeline representation and 81% achieved overall satisfaction. Conclusion: Our study demonstrated the superiority of an AI system in calculating withdrawal time during colonoscopy compared with physicians, providing significant improvements, especially in examinations involving interventions. This work demonstrates the promise of AI in streamlining clinical workflows.

Indexed as

Artificial IntelligenceColonoscopyColorectal NeoplasmsEarly Detection of CancerAgedFemaleHumansMaleMiddle AgedProspective StudiesTime FactorsVideo Recording

Identifiers

PMID41082920
PMCPMC13063404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.