Evidence map›Paper›PMID 41082871›Full record

Observational studyClinical gerontologist

Pain, Depression, and Functional Outcomes Among Older Adults Who Use Cannabis or Opioid Analgesics for Chronic Pain Conditions.

Jonathan H Aebischer, Lyndsey M Anderson, Nathan F Dieckmann, Nora C Mattek, Jeffrey A Kaye

Abstract readObservational Study
In one paragraph

Observational study in Clinical gerontologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan H AebischerSchool of Nursing, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
Lyndsey M AndersonSchool of Nursing, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
Nathan F DieckmannSchool of Nursing, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
Nora C MattekLayton Aging and Alzheimer's Disease Center and Oregon Center for Aging and Technology, OHSU, Portland, Oregon, USA.
Jeffrey A KayeLayton Aging and Alzheimer's Disease Center and Oregon Center for Aging and Technology, OHSU, Portland, Oregon, USA.

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Zachary Beattie · 2020 to 2026
$28.6M
Pilot CoreP30AG024978 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 2004 to 2023
$9.0M
Resource CoreU2CAG054397 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 2016 to 2019
$7.0M
Intelligent Systems for Detection of Aging ChangesR01AG024059 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 2006 to 2010
$6.7M
Racial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6M
NCATS NIH HHS UL1 TR002369NIA NIH HHS P30 AG010161NIA NIH HHS P30 AG024978NIA NIH HHS P30 AG066518NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG024059NIA NIH HHS RF1 AG022018NIA NIH HHS U2C AG054397
6 · The paper itself

Abstract

objectivesThe objectives of this study were to estimate the proportions of older adults with chronic, non-cancer pain (CNCP) who use cannabis or prescription opioids, and their pain, function, and measures of depression over time.

methodsThis was a longitudinal, observational secondary analysis of older adults enrolled in the Oregon Center for Aging and Technology study with pain for ≥12 weeks. Predictors were cannabis and opioid use at weekly intervals. Outcomes were weekly pain intensity, pain interference, feeling blue, physical limitations, and annual Geriatric Depression Scale scores.

resultsAbout 353 participants met criteria with 5% using cannabis and 11% opioids. After controlling for confounders, cannabis use was associated with more pain interference and depression symptoms over time. Opioid use was associated with more pain intensity and interference.

conclusionsCannabis was associated with more pain interference and symptoms of depression. Findings were limited by a small sample. Longitudinal data with reliable measures are needed.

Indexed as

Analgesics, OpioidChronic PainDepressionMedical MarijuanaAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedOregonPain MeasurementAnalgesics, OpioidMedical MarijuanaCannabischronic paindepressionphysical function

Identifiers

PMID41082871
PMCPMC12997168

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.