Evidence map›Paper›PMID 41082590›Full record

SynthesisJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Distal Femoral Varus Osteotomy in Valgus Knee With Lateral Compartment Osteoarthritis: A Systematic Review.

Hamidreza Yazdi, Ali Torkaman, Reza Sahrai, Mohammad Javad Raygani, Amir Reza Makhmalbaf, Mohsen Fathi

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamidreza YazdiFrom the Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran (Dr. Yazdi, Dr. Torkaman, Dr. Sahrai, Dr. Raygani, Dr. Makhmalbaf, and Dr. Fathi), Firoozgar General Hospital, Iran University of Medical Sciences, Tehran, Iran (Dr. Yazdi, Dr. Torkaman, and Dr. Fathi).
Ali Torkaman
Reza Sahrai
Mohammad Javad Raygani
Amir Reza Makhmalbaf

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe precise role of distal femoral varus osteotomy (DFVO) in managing lateral compartment gonarthrosis remains incompletely defined, particularly concerning the extent of joint degeneration that supports or contraindicates the procedure at different stages of arthritis. This systematic review synthesizes recent comparative studies to evaluate the indications, functional outcomes, survivorship rates, and complication profiles associated with both closing wedge and opening wedge techniques. Given the scarcity of controlled trials and direct comparative analyses, this review aims to provide evidence-based insights into the clinical efficacy of DFVO.

methodsThis systematic review evaluated studies primarily focused on DFVO for valgus knees with lateral compartment osteoarthritis, published in PubMed, Medline, Embase, or Cochrane databases since 2000. Only English-language studies reporting clinical outcomes with a minimum follow-up of 2 years in human patients were included. After duplicate removal and screening-based on title, abstract, and full-text review, following the Preferred Reporting Items for Systematic Reviews and Meta-analyses methodology-the methodologic quality of the included studies was assessed using the Newcastle-Ottawa Scale.

resultsA total of 18 studies met the inclusion criteria, with six evaluating closing wedge DFVO and 12 focusing on opening wedge DFVO. Among these studies, the highest reported conversion rate to total knee arthroplasty was 48.4%, with lateral cortex injury identified as the most common complication. Two studies reported no minor or major complications. Long-term clinical and radiologic follow-up, along with functional assessments, demonstrated substantial efficacy and acceptable safety for DFVO. The reported survival rates at 5, 10, and 15 years ranged from 74% to 88%, 74% to 90%, and 45% to 79%, respectively. DISCUSSION: This systematic review indicates that DFVO provides acceptable long-term survival, favorable functional outcomes, and a manageable complication profile, supporting its role as a viable treatment option for valgus knees with lateral compartment osteoarthritis. Recent studies suggest that when osteotomy is done at the precise site of the deformity, both closing wedge and opening wedge techniques achieve comparable survivorship rates.

conclusionCurrent evidence supports that DFVO yields favorable functional outcomes and acceptable survival rates in the management of valgus knee osteoarthritis affecting the lateral compartment. When performed at the precise site of deformity, both closing wedge and opening wedge techniques exhibit comparable survivorship and functional results. Additional randomized studies are necessary to refine surgical techniques and optimize patient selection criteria.

Indexed as

FemurKnee JointOsteoarthritis, KneeOsteotomyHumansTreatment Outcome

Identifiers

PMID41082590
PMCPMC12513449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.