Evidence map›Paper›PMID 41082442›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Electrosensitive Heterogeneous Short Fibers via Acousto-Electric Coupling for Sequential Bone Regeneration in Infectious Defects.

Xiaoyu Han, Fan Wang, Pengcheng Xiao, Zheng Yang, Mingyue Liu, Zeyu Han, Zijie Wang, Anan Jiang, Jindong Tan, Juan Wang and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoyu HanDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Fan WangDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.
Pengcheng XiaoDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Zheng YangDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Mingyue LiuDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.
Zeyu HanDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.
Zijie WangDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Anan JiangDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Jindong TanDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.
Juan WangDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.
Wenguo CuiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.ORCID https://orcid.org/0000-0002-6938-9582
Dingqun BaiDepartment of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, P. R. China.

Funding

Chongqing Natural Science Foundation CSTB2025NSCO-GPX1126Chongqing Natural Science Foundation Innovation and Development Joint Fund CSTB2023NSCQ-LZX006Chongqing Science and Health Joint Medical Research Key Project 2024ZDXM005National Natural Science Foundation of China 32501202National Natural Science Foundation of China 82172533National Natural Science Foundation of China 82372572National Natural Science Foundation of China 82502585National Natural Science Foundation of China 82572940National Natural Science Foundation of China W2411085Postdoctoral Fellowship Program and China Postdoctoral Science Foundation 2023M742360Postdoctoral Fellowship Program and China Postdoctoral Science Foundation 2024M763902Postdoctoral Fellowship Program and China Postdoctoral Science Foundation 2025T180789Postdoctoral Fellowship Program and China Postdoctoral Science Foundation BX20230228Postdoctoral Fellowship Program and China Postdoctoral Science Foundation BX20240454Science and Technology Innovation Action Plan" Domestic Science and Technology Cooperation Project of Shanghai 23015820800Shanghai Oriental Talent Program QNW2024075Shanghai Science and Technology Program 24YF2739200Shanghai Science and Technology Program 24YF2739500
6 · The paper itself

Abstract

The disruption of dynamic equilibrium between antimicrobial and osteogenic processes, caused by the heterogeneous electro-sensitivity of bacteria and host cells, is central to the high failure rate in repairing infected bone defects. This study collected clinical data and systematically analyzed the limitations of electrical stimulation in bone repair. Consequently, electrosensitive heterogeneous short fibers are innovatively developed, achieving sequential regeneration of infected bone defects through acousto-electric coupling. First, barium titanate nanoparticles with excellent piezoelectric properties are synthesized by ion substitution doping (BaTiO

Indexed as

Bone RegenerationAnimalsBarium CompoundsGraphiteHumansIndolesMesenchymal Stem CellsOsteogenesisPolymersTitaniumBarium Compoundsbarium titanate(IV)graphene oxideGraphiteIndolespolydopaminePolymersTitaniumacoustic‐electric couplingbone defectelectro‐sensitivityosteogenesisultrasound

Identifiers

PMID41082442
PMCPMC12752602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.